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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYA
All Species:
7.27
Human Site:
S263
Identified Species:
17.78
UniProt:
Q5MJ70
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ70
NP_001008779.1
313
36463
S263
T
E
K
H
S
Q
D
S
Y
N
S
L
S
M
D
Chimpanzee
Pan troglodytes
XP_515374
225
26070
Y176
E
K
H
S
Q
D
S
Y
N
S
L
S
M
D
I
Rhesus Macaque
Macaca mulatta
XP_001102674
313
36653
S263
T
E
K
H
S
Q
E
S
Y
N
S
L
S
M
D
Dog
Lupus familis
XP_533235
197
22566
D148
A
D
F
L
H
Q
R
D
K
L
W
A
R
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
Q260
E
L
M
E
K
G
S
Q
E
L
H
S
A
F
S
Rat
Rattus norvegicus
Q8R496
312
36205
L262
T
G
K
R
S
Q
E
L
H
N
S
L
S
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
S262
E
N
H
E
A
Q
E
S
P
T
T
L
P
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
N240
S
G
G
V
S
H
N
N
S
S
S
P
E
Q
E
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
P238
P
R
P
S
S
A
G
P
R
S
S
S
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
R217
D
A
T
P
V
H
C
R
A
C
E
K
A
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
97.4
28.4
N.A.
83.3
85.9
N.A.
69.3
N.A.
39.6
49.8
N.A.
N.A.
N.A.
N.A.
42.8
Protein Similarity:
100
71.8
98.7
38.6
N.A.
90
91
N.A.
80.8
N.A.
55.9
64.8
N.A.
N.A.
N.A.
N.A.
59.4
P-Site Identity:
100
0
93.3
13.3
N.A.
0
66.6
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
20
N.A.
6.6
80
N.A.
46.6
N.A.
46.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
10
0
0
10
0
0
10
30
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
10
10
10
0
0
0
0
0
10
30
% D
% Glu:
30
20
0
20
0
0
30
0
10
0
10
0
10
10
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
20
10
0
0
10
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
20
20
10
20
0
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
30
0
10
0
0
0
10
0
0
10
0
0
0
% K
% Leu:
0
10
0
10
0
0
0
10
0
20
10
40
0
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
40
0
% M
% Asn:
0
10
0
0
0
0
10
10
10
30
0
0
0
0
0
% N
% Pro:
10
0
10
10
0
0
0
10
10
0
0
10
10
10
0
% P
% Gln:
0
0
0
0
10
50
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
10
0
10
0
0
10
10
10
0
0
0
10
0
10
% R
% Ser:
10
0
0
20
50
0
20
30
10
30
50
30
30
0
20
% S
% Thr:
30
0
10
0
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _