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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPDYA All Species: 8.18
Human Site: T256 Identified Species: 20
UniProt: Q5MJ70 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5MJ70 NP_001008779.1 313 36463 T256 S S H T A G V T E K H S Q D S
Chimpanzee Pan troglodytes XP_515374 225 26070 E169 S H T A G V T E K H S Q D S Y
Rhesus Macaque Macaca mulatta XP_001102674 313 36653 T256 S S H T S G V T E K H S Q E S
Dog Lupus familis XP_533235 197 22566 A141 K D W R C R V A D F L H Q R D
Cat Felis silvestris
Mouse Mus musculus Q5IBH7 310 36038 E253 S S S S D T G E L M E K G S Q
Rat Rattus norvegicus Q8R496 312 36205 T255 S S D I V E L T G K R S Q E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509302 311 36120 E255 S S L L E L I E N H E A Q E S
Chicken Gallus gallus
Frog Xenopus laevis Q9PU13 299 34670 S233 H K A G V C D S G G V S H N N
Zebra Danio Brachydanio rerio NP_001006091 289 33220 P231 K T S A L P V P R P S S A G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782631 266 30955 D210 E A I P M G P D A T P V H C R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.8 97.4 28.4 N.A. 83.3 85.9 N.A. 69.3 N.A. 39.6 49.8 N.A. N.A. N.A. N.A. 42.8
Protein Similarity: 100 71.8 98.7 38.6 N.A. 90 91 N.A. 80.8 N.A. 55.9 64.8 N.A. N.A. N.A. N.A. 59.4
P-Site Identity: 100 6.6 86.6 13.3 N.A. 13.3 40 N.A. 26.6 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 20 N.A. 20 53.3 N.A. 46.6 N.A. 26.6 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 20 10 0 0 10 10 0 0 10 10 0 0 % A
% Cys: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 10 10 0 10 0 10 10 10 0 0 0 10 10 10 % D
% Glu: 10 0 0 0 10 10 0 30 20 0 20 0 0 30 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 10 10 30 10 0 20 10 0 0 10 10 0 % G
% His: 10 10 20 0 0 0 0 0 0 20 20 10 20 0 0 % H
% Ile: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 20 10 0 0 0 0 0 0 10 30 0 10 0 0 0 % K
% Leu: 0 0 10 10 10 10 10 0 10 0 10 0 0 0 10 % L
% Met: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % N
% Pro: 0 0 0 10 0 10 10 10 0 10 10 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 50 0 10 % Q
% Arg: 0 0 0 10 0 10 0 0 10 0 10 0 0 10 10 % R
% Ser: 60 50 20 10 10 0 0 10 0 0 20 50 0 20 30 % S
% Thr: 0 10 10 20 0 10 10 30 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 20 10 40 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _