KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYA
All Species:
11.52
Human Site:
T280
Identified Species:
28.15
UniProt:
Q5MJ70
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ70
NP_001008779.1
313
36463
T280
G
D
P
S
Q
A
Y
T
G
S
E
V
V
N
D
Chimpanzee
Pan troglodytes
XP_515374
225
26070
G193
D
P
S
Q
A
Y
T
G
S
E
V
V
N
D
H
Rhesus Macaque
Macaca mulatta
XP_001102674
313
36653
T280
D
D
P
S
Q
A
Y
T
S
S
Q
V
V
N
D
Dog
Lupus familis
XP_533235
197
22566
C165
A
M
V
S
R
Q
C
C
E
E
V
M
A
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
T277
T
A
G
D
P
P
H
T
Y
S
Q
V
A
N
D
Rat
Rattus norvegicus
Q8R496
312
36205
T279
G
D
P
S
Q
A
N
T
Y
S
Q
V
A
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
C279
Y
E
P
S
Q
F
Y
C
S
Q
V
P
Y
E
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
S257
H
Y
T
N
R
E
W
S
Q
E
L
L
M
L
S
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
K255
K
A
S
H
R
A
S
K
T
T
K
A
Q
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
Q234
L
N
S
T
S
S
L
Q
N
H
T
F
L
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
97.4
28.4
N.A.
83.3
85.9
N.A.
69.3
N.A.
39.6
49.8
N.A.
N.A.
N.A.
N.A.
42.8
Protein Similarity:
100
71.8
98.7
38.6
N.A.
90
91
N.A.
80.8
N.A.
55.9
64.8
N.A.
N.A.
N.A.
N.A.
59.4
P-Site Identity:
100
6.6
80
6.6
N.A.
33.3
73.3
N.A.
26.6
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
86.6
26.6
N.A.
46.6
80
N.A.
40
N.A.
40
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
10
40
0
0
0
0
0
10
30
0
0
% A
% Cys:
0
0
0
0
0
0
10
20
0
0
0
0
0
0
0
% C
% Asp:
20
30
0
10
0
0
0
0
0
0
0
0
0
10
50
% D
% Glu:
0
10
0
0
0
10
0
0
10
30
10
0
0
10
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
20
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
10
0
0
10
0
0
10
0
0
10
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
10
10
10
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
10
0
10
0
0
10
0
10
0
0
0
10
40
10
% N
% Pro:
0
10
40
0
10
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
40
10
0
10
10
10
30
0
10
0
0
% Q
% Arg:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
30
50
10
10
10
10
30
40
0
0
0
0
10
% S
% Thr:
10
0
10
10
0
0
10
40
10
10
10
0
0
10
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
30
50
20
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
10
30
0
20
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _