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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYA
All Species:
8.79
Human Site:
Y237
Identified Species:
21.48
UniProt:
Q5MJ70
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ70
NP_001008779.1
313
36463
Y237
L
C
G
K
K
R
R
Y
V
R
L
G
L
S
S
Chimpanzee
Pan troglodytes
XP_515374
225
26070
V150
C
G
K
K
R
R
Y
V
R
L
G
L
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001102674
313
36653
Y237
L
C
G
K
K
R
R
Y
V
R
L
G
L
S
S
Dog
Lupus familis
XP_533235
197
22566
D122
D
M
E
E
D
L
E
D
P
K
C
V
I
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
G234
C
S
L
C
G
K
K
G
R
Y
V
R
L
G
L
Rat
Rattus norvegicus
Q8R496
312
36205
Y236
L
C
G
K
K
G
R
Y
V
R
L
G
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
V236
L
C
G
K
K
R
C
V
E
L
G
L
S
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
G214
E
D
D
F
S
P
R
G
P
G
L
T
P
A
S
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
P212
E
I
L
V
P
R
G
P
A
A
S
P
E
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
A191
R
M
P
H
H
A
G
A
V
R
K
Y
P
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
97.4
28.4
N.A.
83.3
85.9
N.A.
69.3
N.A.
39.6
49.8
N.A.
N.A.
N.A.
N.A.
42.8
Protein Similarity:
100
71.8
98.7
38.6
N.A.
90
91
N.A.
80.8
N.A.
55.9
64.8
N.A.
N.A.
N.A.
N.A.
59.4
P-Site Identity:
100
26.6
100
0
N.A.
6.6
93.3
N.A.
53.3
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
33.3
100
20
N.A.
26.6
93.3
N.A.
53.3
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
10
10
0
0
0
10
0
% A
% Cys:
20
40
0
10
0
0
10
0
0
0
10
0
0
0
10
% C
% Asp:
10
10
10
0
10
0
0
10
0
0
0
0
0
10
0
% D
% Glu:
20
0
10
10
0
0
10
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
40
0
10
10
20
20
0
10
20
30
0
10
0
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
50
40
10
10
0
0
10
10
0
0
0
0
% K
% Leu:
40
0
20
0
0
10
0
0
0
20
40
20
40
0
20
% L
% Met:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
10
0
10
20
0
0
10
20
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
50
40
0
20
40
0
10
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
0
0
0
10
0
20
50
60
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
20
40
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
30
0
10
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _