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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45L
All Species:
35.45
Human Site:
S268
Identified Species:
55.71
UniProt:
Q5MNZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ6
NP_062559.2
344
38122
S268
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Chimpanzee
Pan troglodytes
XP_511805
344
38432
S268
D
L
K
R
N
K
Q
S
S
L
A
S
A
S
F
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
S250
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Dog
Lupus familis
XP_537936
450
49722
S374
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR39
344
38002
S268
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Rat
Rattus norvegicus
Q5U2Y0
309
34568
P234
A
R
V
G
K
V
G
P
M
I
G
Q
Y
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513548
293
32071
G218
P
F
L
N
N
S
S
G
C
L
I
E
P
P
A
Chicken
Gallus gallus
Q5ZL16
344
38071
S268
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Frog
Xenopus laevis
Q68F45
344
38163
S268
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
S268
D
P
K
R
N
K
Q
S
S
L
A
S
A
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649853
340
37929
P264
F
N
L
E
D
N
K
P
R
E
S
S
L
P
I
Honey Bee
Apis mellifera
XP_396423
343
38254
S267
D
Q
K
L
N
R
Q
S
S
L
A
S
A
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792976
348
38780
K271
A
D
A
Q
K
N
K
K
S
Q
L
A
S
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
N307
E
T
T
N
T
E
T
N
T
P
D
H
S
R
A
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
A298
N
T
Q
K
N
A
N
A
L
P
G
G
G
P
A
Conservation
Percent
Protein Identity:
100
94.4
94.1
73.7
N.A.
99.1
43.9
N.A.
66.8
97.3
96.8
95.6
N.A.
67.7
73.2
N.A.
74.7
Protein Similarity:
100
96.2
94.4
75.1
N.A.
99.7
57.8
N.A.
72.9
98.5
98.5
97.6
N.A.
80.5
85.1
N.A.
86.7
P-Site Identity:
100
93.3
100
100
N.A.
100
0
N.A.
13.3
100
100
100
N.A.
6.6
73.3
N.A.
6.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
6.6
N.A.
13.3
100
100
100
N.A.
26.6
86.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
27.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
42.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
0
7
0
7
0
0
60
7
60
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
60
7
0
0
7
0
0
0
0
0
7
0
0
0
7
% D
% Glu:
7
0
0
7
0
7
0
0
0
7
0
7
0
0
0
% E
% Phe:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
0
0
0
7
0
0
7
7
0
0
14
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
7
% I
% Lys:
0
0
60
7
14
54
14
7
0
0
0
0
0
0
0
% K
% Leu:
0
7
14
7
0
0
0
0
7
67
7
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
7
0
14
74
14
7
7
0
0
0
0
0
0
0
% N
% Pro:
7
47
0
0
0
0
0
14
0
14
0
0
7
20
0
% P
% Gln:
0
7
7
7
0
0
60
0
0
7
0
7
0
0
0
% Q
% Arg:
0
7
0
54
0
7
0
0
7
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
7
7
60
67
0
7
67
14
54
7
% S
% Thr:
0
14
7
0
7
0
7
0
7
0
0
0
0
7
0
% T
% Val:
0
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _