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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45L
All Species:
40
Human Site:
S285
Identified Species:
62.86
UniProt:
Q5MNZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ6
NP_062559.2
344
38122
S285
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Chimpanzee
Pan troglodytes
XP_511805
344
38432
S285
K
Y
F
S
Y
K
W
S
F
S
K
F
Q
V
P
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
S267
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Dog
Lupus familis
XP_537936
450
49722
S391
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR39
344
38002
S285
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Rat
Rattus norvegicus
Q5U2Y0
309
34568
V251
W
S
L
A
S
F
T
V
P
A
E
S
A
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513548
293
32071
F235
K
N
S
L
T
L
G
F
Q
G
S
S
I
T
C
Chicken
Gallus gallus
Q5ZL16
344
38071
S285
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Frog
Xenopus laevis
Q68F45
344
38163
S285
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
S285
K
Y
F
S
S
K
W
S
F
S
K
F
Q
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649853
340
37929
S281
K
Y
F
S
S
Q
W
S
F
V
K
F
S
I
P
Honey Bee
Apis mellifera
XP_396423
343
38254
S284
K
Y
F
S
S
S
W
S
F
C
K
F
Q
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792976
348
38780
W288
P
K
Y
F
N
S
S
W
S
F
C
K
F
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
Y324
S
S
H
P
L
K
N
Y
I
P
K
G
L
W
R
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
V315
T
R
S
R
S
F
D
V
N
D
P
S
P
H
K
Conservation
Percent
Protein Identity:
100
94.4
94.1
73.7
N.A.
99.1
43.9
N.A.
66.8
97.3
96.8
95.6
N.A.
67.7
73.2
N.A.
74.7
Protein Similarity:
100
96.2
94.4
75.1
N.A.
99.7
57.8
N.A.
72.9
98.5
98.5
97.6
N.A.
80.5
85.1
N.A.
86.7
P-Site Identity:
100
93.3
100
100
N.A.
100
6.6
N.A.
6.6
100
100
100
N.A.
73.3
86.6
N.A.
0
P-Site Similarity:
100
93.3
100
100
N.A.
100
26.6
N.A.
13.3
100
100
100
N.A.
86.6
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
27.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
42.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
7
0
0
7
7
% C
% Asp:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
67
7
0
14
0
7
67
7
0
67
7
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
7
7
7
% I
% Lys:
74
7
0
0
0
60
0
0
0
0
74
7
0
0
7
% K
% Leu:
0
0
7
7
7
7
0
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
7
0
0
0
0
7
7
7
0
7
0
67
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
0
0
60
7
0
% Q
% Arg:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
7
14
14
67
74
14
7
67
7
54
7
20
7
0
0
% S
% Thr:
7
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
14
0
7
0
0
0
60
7
% V
% Trp:
7
0
0
0
0
0
67
7
0
0
0
0
0
7
0
% W
% Tyr:
0
67
7
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _