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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR45L All Species: 48.79
Human Site: T202 Identified Species: 76.67
UniProt: Q5MNZ6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5MNZ6 NP_062559.2 344 38122 T202 L Q G T R I A T A S E K G T L
Chimpanzee Pan troglodytes XP_511805 344 38432 T202 L Q G T R I A T A S E K G T L
Rhesus Macaque Macaca mulatta XP_001114123 326 36142 T184 L Q G T R I A T A S E K G T L
Dog Lupus familis XP_537936 450 49722 T308 L Q G T R I A T A S E K G T L
Cat Felis silvestris
Mouse Mus musculus Q9CR39 344 38002 T202 L Q G T R I A T A S E K G T L
Rat Rattus norvegicus Q5U2Y0 309 34568 S168 F P G H K C G S L Q L V S K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513548 293 32071 N152 C V L C P N S N N S L L A F P
Chicken Gallus gallus Q5ZL16 344 38071 T202 L Q G T R I A T A S E K G T L
Frog Xenopus laevis Q68F45 344 38163 T202 L Q G T R I A T A S E K G T L
Zebra Danio Brachydanio rerio Q7ZUW6 344 38148 T202 L Q G T R I A T A S E K G T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649853 340 37929 T198 I A L N L Q G T R L A T A G E
Honey Bee Apis mellifera XP_396423 343 38254 T201 L Q G T R L A T A S E K G T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792976 348 38780 T205 H Q G S R L A T A S D R G T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50079 448 51217 T241 R Q G T M V A T C S V Q G T L
Red Bread Mold Neurospora crassa Q96U88 461 50001 T232 H D G S M L A T A S E T G T I
Conservation
Percent
Protein Identity: 100 94.4 94.1 73.7 N.A. 99.1 43.9 N.A. 66.8 97.3 96.8 95.6 N.A. 67.7 73.2 N.A. 74.7
Protein Similarity: 100 96.2 94.4 75.1 N.A. 99.7 57.8 N.A. 72.9 98.5 98.5 97.6 N.A. 80.5 85.1 N.A. 86.7
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 6.6 100 100 100 N.A. 6.6 93.3 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 13.3 100 100 100 N.A. 13.3 100 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31 27.3
Protein Similarity: N.A. N.A. N.A. N.A. 47.7 42.9
P-Site Identity: N.A. N.A. N.A. N.A. 60 53.3
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 80 0 74 0 7 0 14 0 0 % A
% Cys: 7 0 0 7 0 7 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 14 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 87 0 0 0 14 0 0 0 0 0 80 7 0 % G
% His: 14 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 54 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 7 0 0 0 0 0 0 60 0 7 0 % K
% Leu: 60 0 14 0 7 20 0 0 7 7 14 7 0 0 74 % L
% Met: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 7 7 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 74 0 0 0 7 0 0 0 7 0 7 0 0 0 % Q
% Arg: 7 0 0 0 67 0 0 0 7 0 0 7 0 0 0 % R
% Ser: 0 0 0 14 0 0 7 7 0 87 0 0 7 0 0 % S
% Thr: 0 0 0 67 0 0 0 87 0 0 0 14 0 80 0 % T
% Val: 0 7 0 0 0 7 0 0 0 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _