KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45L
All Species:
36.67
Human Site:
Y15
Identified Species:
57.62
UniProt:
Q5MNZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ6
NP_062559.2
344
38122
Y15
P
H
G
N
G
L
L
Y
A
G
F
N
Q
D
H
Chimpanzee
Pan troglodytes
XP_511805
344
38432
Y15
H
H
R
N
G
L
L
Y
A
G
F
D
Q
D
H
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
E12
G
C
F
A
C
G
M
E
N
G
F
R
V
Y
N
Dog
Lupus familis
XP_537936
450
49722
T79
E
R
V
F
G
R
S
T
A
I
P
D
S
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR39
344
38002
Y15
P
H
G
N
G
L
L
Y
A
G
F
N
Q
D
H
Rat
Rattus norvegicus
Q5U2Y0
309
34568
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513548
293
32071
Chicken
Gallus gallus
Q5ZL16
344
38071
Y15
P
H
G
N
G
L
L
Y
A
G
F
N
Q
D
H
Frog
Xenopus laevis
Q68F45
344
38163
Y15
P
H
G
N
G
L
L
Y
S
G
F
N
Q
D
H
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
Y15
P
H
G
N
G
L
L
Y
A
G
F
N
Q
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649853
340
37929
Y15
P
Y
G
N
G
L
L
Y
A
A
F
N
Q
D
Q
Honey Bee
Apis mellifera
XP_396423
343
38254
Y15
P
H
G
N
G
L
L
Y
A
G
F
N
Q
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792976
348
38780
Y18
S
Y
D
N
S
L
L
Y
A
G
F
N
Q
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
S21
R
R
K
P
K
F
L
S
V
S
F
N
Q
D
D
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
F8
M
T
G
G
T
L
N
F
I
T
F
N
Q
D
Y
Conservation
Percent
Protein Identity:
100
94.4
94.1
73.7
N.A.
99.1
43.9
N.A.
66.8
97.3
96.8
95.6
N.A.
67.7
73.2
N.A.
74.7
Protein Similarity:
100
96.2
94.4
75.1
N.A.
99.7
57.8
N.A.
72.9
98.5
98.5
97.6
N.A.
80.5
85.1
N.A.
86.7
P-Site Identity:
100
80
13.3
13.3
N.A.
100
0
N.A.
0
100
93.3
100
N.A.
80
93.3
N.A.
66.6
P-Site Similarity:
100
86.6
26.6
26.6
N.A.
100
0
N.A.
0
100
100
100
N.A.
86.6
93.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
27.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
42.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
60
7
0
0
0
0
0
% A
% Cys:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
14
0
74
7
% D
% Glu:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
7
0
7
0
7
0
0
80
0
0
0
0
% F
% Gly:
7
0
54
7
60
7
0
0
0
60
0
0
0
0
0
% G
% His:
7
47
0
0
0
0
0
0
0
0
0
0
0
0
40
% H
% Ile:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
67
67
0
0
0
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
60
0
0
7
0
7
0
0
67
0
0
14
% N
% Pro:
47
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
74
0
14
% Q
% Arg:
7
14
7
0
0
7
0
0
0
0
0
7
0
0
0
% R
% Ser:
7
0
0
0
7
0
7
7
7
7
0
0
7
0
0
% S
% Thr:
0
7
0
0
7
0
0
7
0
7
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
7
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
0
0
0
60
0
0
0
0
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _