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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45L
All Species:
44.24
Human Site:
Y234
Identified Species:
69.52
UniProt:
Q5MNZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ6
NP_062559.2
344
38122
Y234
G
S
Q
A
A
N
I
Y
C
I
N
F
N
Q
D
Chimpanzee
Pan troglodytes
XP_511805
344
38432
Y234
G
S
Q
A
A
N
I
Y
C
I
N
F
N
Q
D
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
Y216
G
S
Q
A
A
N
I
Y
C
I
N
F
N
Q
D
Dog
Lupus familis
XP_537936
450
49722
Y340
G
S
Q
A
A
N
I
Y
C
I
N
F
N
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR39
344
38002
Y234
G
S
Q
A
A
N
I
Y
C
I
N
F
N
Q
D
Rat
Rattus norvegicus
Q5U2Y0
309
34568
F200
N
F
S
H
D
S
S
F
L
C
A
S
S
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513548
293
32071
H184
P
P
V
D
I
P
A
H
E
G
V
L
S
C
I
Chicken
Gallus gallus
Q5ZL16
344
38071
Y234
G
S
Q
A
A
N
I
Y
C
I
N
F
N
Q
D
Frog
Xenopus laevis
Q68F45
344
38163
Y234
G
S
Q
A
A
N
I
Y
C
I
N
F
N
E
D
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
Y234
G
S
Q
T
A
N
I
Y
C
I
N
F
N
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649853
340
37929
H230
E
L
R
R
G
S
N
H
A
N
I
F
C
I
N
Honey Bee
Apis mellifera
XP_396423
343
38254
Y233
G
A
N
H
A
N
I
Y
C
I
N
F
N
H
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792976
348
38780
Y237
G
S
G
G
A
Q
I
Y
C
I
N
F
N
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
Y273
G
V
D
K
A
D
I
Y
E
M
S
F
S
P
N
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
Y264
G
T
V
P
T
S
I
Y
S
M
S
F
N
L
S
Conservation
Percent
Protein Identity:
100
94.4
94.1
73.7
N.A.
99.1
43.9
N.A.
66.8
97.3
96.8
95.6
N.A.
67.7
73.2
N.A.
74.7
Protein Similarity:
100
96.2
94.4
75.1
N.A.
99.7
57.8
N.A.
72.9
98.5
98.5
97.6
N.A.
80.5
85.1
N.A.
86.7
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
0
100
93.3
93.3
N.A.
6.6
73.3
N.A.
80
P-Site Similarity:
100
100
100
93.3
N.A.
100
20
N.A.
13.3
100
100
93.3
N.A.
33.3
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
27.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
42.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
47
74
0
7
0
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
67
7
0
0
7
7
0
% C
% Asp:
0
0
7
7
7
7
0
0
0
0
0
0
0
7
67
% D
% Glu:
7
0
0
0
0
0
0
0
14
0
0
0
0
7
0
% E
% Phe:
0
7
0
0
0
0
0
7
0
0
0
87
0
0
0
% F
% Gly:
80
0
7
7
7
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
14
0
0
0
14
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
80
0
0
67
7
0
0
7
7
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
7
0
0
0
0
0
0
7
0
0
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
60
7
0
0
7
67
0
74
0
14
% N
% Pro:
7
7
0
7
0
7
0
0
0
0
0
0
0
14
0
% P
% Gln:
0
0
54
0
0
7
0
0
0
0
0
0
0
47
0
% Q
% Arg:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
60
7
0
0
20
7
0
7
0
14
7
20
0
7
% S
% Thr:
0
7
0
7
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
14
0
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _