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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45L
All Species:
40.3
Human Site:
Y318
Identified Species:
63.33
UniProt:
Q5MNZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ6
NP_062559.2
344
38122
Y318
I
C
A
D
G
S
Y
Y
K
F
L
F
N
P
K
Chimpanzee
Pan troglodytes
XP_511805
344
38432
Y318
I
C
A
D
C
S
Y
Y
K
L
L
F
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
Y300
I
C
A
D
G
S
Y
Y
K
F
L
F
N
P
K
Dog
Lupus familis
XP_537936
450
49722
Y424
I
C
A
D
G
S
Y
Y
K
F
L
F
N
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR39
344
38002
Y318
I
C
A
D
G
S
Y
Y
K
F
L
F
S
P
K
Rat
Rattus norvegicus
Q5U2Y0
309
34568
Y284
V
D
G
T
F
H
K
Y
V
F
T
P
D
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513548
293
32071
D268
V
H
I
F
A
A
E
D
P
K
R
N
K
Q
S
Chicken
Gallus gallus
Q5ZL16
344
38071
Y318
I
C
A
D
G
S
Y
Y
K
F
L
F
N
Q
K
Frog
Xenopus laevis
Q68F45
344
38163
Y318
I
C
A
D
G
S
Y
Y
K
F
Q
F
N
P
K
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
Y318
I
C
A
D
G
S
Y
Y
K
F
L
F
N
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649853
340
37929
Y314
I
C
A
D
G
H
Y
Y
K
F
L
F
N
N
K
Honey Bee
Apis mellifera
XP_396423
343
38254
Y317
I
C
A
D
G
S
Y
Y
K
F
V
F
N
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792976
348
38780
Y321
A
I
C
A
D
G
S
Y
F
K
F
V
F
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
D357
I
F
D
A
H
R
N
D
N
S
G
D
V
T
H
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
N348
E
P
S
G
S
F
G
N
M
L
R
R
S
S
Q
Conservation
Percent
Protein Identity:
100
94.4
94.1
73.7
N.A.
99.1
43.9
N.A.
66.8
97.3
96.8
95.6
N.A.
67.7
73.2
N.A.
74.7
Protein Similarity:
100
96.2
94.4
75.1
N.A.
99.7
57.8
N.A.
72.9
98.5
98.5
97.6
N.A.
80.5
85.1
N.A.
86.7
P-Site Identity:
100
86.6
100
100
N.A.
93.3
13.3
N.A.
0
93.3
93.3
100
N.A.
86.6
86.6
N.A.
6.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
26.6
N.A.
13.3
93.3
93.3
100
N.A.
86.6
93.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
27.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
42.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
67
14
7
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
67
7
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
67
7
0
0
14
0
0
0
7
7
0
0
% D
% Glu:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
7
7
7
0
0
7
67
7
67
7
0
0
% F
% Gly:
0
0
7
7
60
7
7
0
0
0
7
0
0
7
0
% G
% His:
0
7
0
0
7
14
0
0
0
0
0
0
0
0
7
% H
% Ile:
74
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
67
14
0
0
7
0
67
% K
% Leu:
0
0
0
0
0
0
0
0
0
14
54
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
7
0
0
7
60
20
7
% N
% Pro:
0
7
0
0
0
0
0
0
7
0
0
7
0
47
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
14
7
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
14
7
0
0
0
% R
% Ser:
0
0
7
0
7
60
7
0
0
7
0
0
14
7
14
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% T
% Val:
14
0
0
0
0
0
0
0
7
0
7
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
67
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _