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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45L
All Species:
44.55
Human Site:
Y65
Identified Species:
70
UniProt:
Q5MNZ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ6
NP_062559.2
344
38122
Y65
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Chimpanzee
Pan troglodytes
XP_511805
344
38432
Y65
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
Y47
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Dog
Lupus familis
XP_537936
450
49722
Y171
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR39
344
38002
Y65
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Rat
Rattus norvegicus
Q5U2Y0
309
34568
V34
T
G
V
R
I
Y
N
V
E
P
L
M
E
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513548
293
32071
F18
N
G
L
L
Y
A
G
F
N
Q
D
H
G
C
F
Chicken
Gallus gallus
Q5ZL16
344
38071
Y65
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Frog
Xenopus laevis
Q68F45
344
38163
Y65
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
Y65
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649853
340
37929
N64
V
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
Honey Bee
Apis mellifera
XP_396423
343
38254
Y64
E
M
L
F
R
C
N
Y
L
A
L
V
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792976
348
38780
Y68
E
M
L
F
R
C
N
Y
L
A
L
V
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
Y79
R
M
L
Y
R
T
N
Y
I
A
L
V
G
G
G
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
D74
E
I
Q
N
T
K
V
D
Q
P
S
Q
R
H
C
Conservation
Percent
Protein Identity:
100
94.4
94.1
73.7
N.A.
99.1
43.9
N.A.
66.8
97.3
96.8
95.6
N.A.
67.7
73.2
N.A.
74.7
Protein Similarity:
100
96.2
94.4
75.1
N.A.
99.7
57.8
N.A.
72.9
98.5
98.5
97.6
N.A.
80.5
85.1
N.A.
86.7
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
13.3
100
100
100
N.A.
13.3
93.3
N.A.
100
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
20
100
100
100
N.A.
26.6
93.3
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
27.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
42.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
74
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
67
7
0
0
0
0
0
0
7
7
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% D
% Glu:
74
7
0
0
0
0
0
0
7
0
0
0
7
0
0
% E
% Phe:
0
0
0
67
7
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
14
0
0
0
0
7
0
0
0
0
0
80
74
87
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% H
% Ile:
0
7
0
0
7
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
0
80
14
0
0
0
0
67
7
80
7
0
0
0
% L
% Met:
0
74
7
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
7
0
0
80
7
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
7
7
0
7
0
0
0
% Q
% Arg:
7
0
0
7
74
7
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% S
% Thr:
7
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
7
0
0
0
7
7
0
0
0
74
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
0
74
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _