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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIPI1 All Species: 4.55
Human Site: S335 Identified Species: 9.09
UniProt: Q5MNZ9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5MNZ9 NP_060453.3 446 48673 S335 R L L V A S S S G H L Y M Y N
Chimpanzee Pan troglodytes XP_001165276 446 48667 S335 R L L V A S S S G H L Y M Y N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548021 479 51996 D368 R L L V A S S D G H L Y I Y N
Cat Felis silvestris
Mouse Mus musculus Q8R3E3 446 48740 D335 R L L V A S S D G H L Y I Y N
Rat Rattus norvegicus Q6AY57 445 48501 D333 R L L V G A S D G Y L Y M Y N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512711 416 45669 A319 I P R L L V G A S D G Y L Y M
Chicken Gallus gallus Q5ZHN3 436 47757 D333 R L L V G A A D G Y L Y M Y N
Frog Xenopus laevis Q6DCN1 433 47366 G331 L L V T S S S G H L Y V Y N L
Zebra Danio Brachydanio rerio Q7ZUW6 344 38148 V247 Q D A S L I C V S S D H G T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624581 392 43147 D295 Y L P S Q V T D V F N Q G R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781358 486 52131 G331 V L V A A A D G F I Y I Y N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q96U88 461 50001 V364 M V R G V A G V A S S Y L P Q
Conservation
Percent
Protein Identity: 100 99.7 N.A. 87.4 N.A. 94.3 55.3 N.A. 55.8 57.1 74.4 25.5 N.A. N.A. 50 N.A. 49.7
Protein Similarity: 100 99.7 N.A. 90.6 N.A. 97.7 70.8 N.A. 71 73 82.5 41.9 N.A. N.A. 64.5 N.A. 64.2
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 73.3 N.A. 13.3 66.6 20 0 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 86.6 N.A. 33.3 86.6 33.3 13.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 25.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 44.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 42 34 9 9 9 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 42 0 9 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % F
% Gly: 0 0 0 9 17 0 17 17 50 0 9 0 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 34 0 9 0 0 0 % H
% Ile: 9 0 0 0 0 9 0 0 0 9 0 9 17 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 75 50 9 17 0 0 0 0 9 50 0 17 0 17 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 34 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 0 17 50 % N
% Pro: 0 9 9 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 9 % Q
% Arg: 50 0 17 0 0 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 17 9 42 50 17 17 17 9 0 0 0 0 % S
% Thr: 0 0 0 9 0 0 9 0 0 0 0 0 0 9 0 % T
% Val: 9 9 17 50 9 17 0 17 9 0 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 17 17 67 17 59 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _