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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIPI1 All Species: 29.09
Human Site: Y156 Identified Species: 58.18
UniProt: Q5MNZ9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5MNZ9 NP_060453.3 446 48673 Y156 S I N H S N S Y L A Y P G S L
Chimpanzee Pan troglodytes XP_001165276 446 48667 Y156 S I N H S N S Y L A Y P G S L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548021 479 51996 Y189 S I N H S N S Y V A Y P G S L
Cat Felis silvestris
Mouse Mus musculus Q8R3E3 446 48740 Y156 S I N H S N S Y L A Y P G S Q
Rat Rattus norvegicus Q6AY57 445 48501 Y154 S I N N D N C Y L A Y P G S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512711 416 45669 N140 A L S I N N D N C Y L A Y P G
Chicken Gallus gallus Q5ZHN3 436 47757 Y154 S I N N D N C Y L A Y P G S A
Frog Xenopus laevis Q6DCN1 433 47366 Y152 S I N H S N S Y L A Y P G S S
Zebra Danio Brachydanio rerio Q7ZUW6 344 38148 L68 F R C N Y L A L V G G G K K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624581 392 43147 S116 L V V C L E E S L Y I H N I R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781358 486 52131 Y152 S I N N D N C Y L A Y P G S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q96U88 461 50001 P185 K A P A H L P P P S Q Y V P P
Conservation
Percent
Protein Identity: 100 99.7 N.A. 87.4 N.A. 94.3 55.3 N.A. 55.8 57.1 74.4 25.5 N.A. N.A. 50 N.A. 49.7
Protein Similarity: 100 99.7 N.A. 90.6 N.A. 97.7 70.8 N.A. 71 73 82.5 41.9 N.A. N.A. 64.5 N.A. 64.2
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 73.3 N.A. 6.6 73.3 93.3 0 N.A. N.A. 6.6 N.A. 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 80 N.A. 33.3 80 93.3 20 N.A. N.A. 13.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 25.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 44.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 0 0 9 0 0 67 0 9 0 0 17 % A
% Cys: 0 0 9 9 0 0 25 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 25 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 9 9 67 0 9 % G
% His: 0 0 0 42 9 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 67 0 9 0 0 0 0 0 0 9 0 0 9 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % K
% Leu: 9 9 0 0 9 17 0 9 67 0 9 0 0 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 67 34 9 75 0 9 0 0 0 0 9 0 0 % N
% Pro: 0 0 9 0 0 0 9 9 9 0 0 67 0 17 17 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % Q
% Arg: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 67 0 9 0 42 0 42 9 0 9 0 0 0 67 17 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 9 9 0 0 0 0 0 17 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 67 0 17 67 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _