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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPI1
All Species:
18.18
Human Site:
Y223
Identified Species:
36.36
UniProt:
Q5MNZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MNZ9
NP_060453.3
446
48673
Y223
V
P
D
G
Q
K
L
Y
E
F
R
R
G
M
K
Chimpanzee
Pan troglodytes
XP_001165276
446
48667
Y223
V
P
D
G
Q
K
L
Y
E
F
R
R
G
M
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548021
479
51996
Y256
V
P
D
G
Q
K
L
Y
E
F
R
R
G
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3E3
446
48740
Y223
V
P
E
G
Q
K
L
Y
E
F
R
R
G
M
K
Rat
Rattus norvegicus
Q6AY57
445
48501
F221
I
P
E
G
Q
K
L
F
E
F
R
R
G
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512711
416
45669
K207
F
S
I
P
E
G
Q
K
L
F
E
F
R
R
G
Chicken
Gallus gallus
Q5ZHN3
436
47757
F221
I
P
E
G
Q
K
L
F
E
F
R
R
G
V
K
Frog
Xenopus laevis
Q6DCN1
433
47366
Y219
I
P
D
G
Q
K
L
Y
E
F
R
R
G
M
K
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
F135
N
P
H
Q
L
H
V
F
E
T
C
Y
N
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624581
392
43147
S183
T
M
I
P
A
H
D
S
P
L
A
A
L
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781358
486
52131
F219
I
P
D
G
K
K
L
F
E
F
R
R
G
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
F252
L
P
Q
G
Q
K
L
F
Q
F
R
R
G
T
V
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.4
N.A.
94.3
55.3
N.A.
55.8
57.1
74.4
25.5
N.A.
N.A.
50
N.A.
49.7
Protein Similarity:
100
99.7
N.A.
90.6
N.A.
97.7
70.8
N.A.
71
73
82.5
41.9
N.A.
N.A.
64.5
N.A.
64.2
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
73.3
N.A.
6.6
73.3
93.3
20
N.A.
N.A.
0
N.A.
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
100
100
33.3
N.A.
N.A.
0
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
42
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
0
9
0
0
0
75
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
42
0
84
0
9
0
0
9
% F
% Gly:
0
0
0
75
0
9
0
0
0
0
0
0
75
0
9
% G
% His:
0
0
9
0
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
75
0
9
0
0
0
0
0
0
67
% K
% Leu:
9
0
0
0
9
0
75
0
9
9
0
0
9
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
42
9
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
84
0
17
0
0
0
0
9
0
0
0
0
9
0
% P
% Gln:
0
0
9
9
67
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
75
75
9
9
0
% R
% Ser:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% T
% Val:
34
0
0
0
0
0
9
0
0
0
0
0
0
25
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _