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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD8
All Species:
33.33
Human Site:
T125
Identified Species:
91.67
UniProt:
Q5MY95
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MY95
NP_001028285.1
495
53904
T125
T
P
T
F
L
G
A
T
A
G
M
R
L
L
S
Chimpanzee
Pan troglodytes
XP_001140109
495
53927
T125
T
P
T
F
L
G
A
T
A
G
M
R
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001087078
495
54022
T125
T
P
M
F
L
G
A
T
A
G
M
R
L
L
R
Dog
Lupus familis
XP_548362
495
53960
T122
T
P
L
Y
L
G
A
T
A
G
M
R
L
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0L2
497
54632
T125
T
P
T
F
L
G
S
T
A
G
M
R
L
L
S
Rat
Rattus norvegicus
Q5DRK1
494
54312
T125
T
P
A
F
L
G
A
T
A
G
M
R
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93295
493
54016
T123
T
P
T
Y
L
G
A
T
A
G
M
R
L
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002379
496
54376
T124
T
P
V
Y
L
G
A
T
A
G
M
R
L
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
T131
T
P
V
F
I
F
A
T
A
G
M
R
L
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.5
43.8
N.A.
73.8
74.9
N.A.
N.A.
52.7
N.A.
44.7
N.A.
N.A.
N.A.
23.9
N.A.
Protein Similarity:
100
98.7
97.1
60.2
N.A.
85.9
85.4
N.A.
N.A.
68.2
N.A.
62
N.A.
N.A.
N.A.
41.8
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
100
93.3
N.A.
N.A.
93.3
N.A.
93.3
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
89
0
100
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
67
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
89
0
0
0
100
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
12
0
89
0
0
0
0
0
0
0
100
89
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
100
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
23
% R
% Ser:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
45
% S
% Thr:
100
0
45
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _