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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AER61 All Species: 22.42
Human Site: S65 Identified Species: 49.33
UniProt: Q5NDL2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5NDL2 NP_775925.1 527 62011 S65 A T V C R K D S L C P Y K K H
Chimpanzee Pan troglodytes Q5NDL1 527 62025 S65 A T V C R K D S L C P Y K K H
Rhesus Macaque Macaca mulatta XP_001088832 527 62153 S65 A T V C K K D S L C P Y K K H
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BYW9 527 61427 S65 A S V C R E D S H C P Y K K H
Rat Rattus norvegicus Q5NDL0 527 61505 S65 A S V C R E D S H C P Y K K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510490 527 61681 S65 A M A C K Q D S H C P Y K K H
Chicken Gallus gallus Q5NDL3 535 62849 F73 R C P Y K V G F Y F V L H K Y
Frog Xenopus laevis Q6GQ23 525 61163 L63 A A L C L Q D L H C P Y K Q H
Zebra Danio Brachydanio rerio XP_001921723 519 60675 P60 C K E D P L C P F K V R Q D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608678 520 60064 T58 T N L T G K G T I S S A C W G
Honey Bee Apis mellifera XP_391981 559 65081 N54 V A Q E C R N N T V C P Y K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.1 N.A. N.A. 87.8 86.9 N.A. 82.5 77 68.6 65 N.A. 46.4 45.6 N.A. N.A.
Protein Similarity: 100 99.6 98.6 N.A. N.A. 94.1 94.1 N.A. 90.3 87.4 81 81.5 N.A. 63.1 61.5 N.A. N.A.
P-Site Identity: 100 100 93.3 N.A. N.A. 80 80 N.A. 66.6 6.6 53.3 0 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 80 20 73.3 6.6 N.A. 26.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 19 10 0 0 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 10 10 0 64 10 0 10 0 0 64 10 0 10 0 0 % C
% Asp: 0 0 0 10 0 0 64 0 0 0 0 0 0 10 10 % D
% Glu: 0 0 10 10 0 19 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 10 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 19 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 37 0 0 0 10 0 64 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 28 37 0 0 0 10 0 0 64 73 0 % K
% Leu: 0 0 19 0 10 10 0 10 28 0 0 10 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 10 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 10 0 0 10 0 0 64 10 0 0 0 % P
% Gln: 0 0 10 0 0 19 0 0 0 0 0 0 10 10 0 % Q
% Arg: 10 0 0 0 37 10 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 19 0 0 0 0 0 55 0 10 10 0 0 0 0 % S
% Thr: 10 28 0 10 0 0 0 10 10 0 0 0 0 0 0 % T
% Val: 10 0 46 0 0 10 0 0 0 10 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 10 0 0 0 0 10 0 0 64 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _