KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSL3
All Species:
3.64
Human Site:
S143
Identified Species:
8
UniProt:
Q5NE16
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5NE16
NP_001903
218
25059
S143
P
F
H
M
K
K
S
S
G
D
W
K
V
Q
G
Chimpanzee
Pan troglodytes
XP_001137800
299
33813
V185
K
Y
N
P
K
Y
S
V
A
N
D
T
G
F
V
Rhesus Macaque
Macaca mulatta
XP_001086024
333
37445
V219
K
Y
N
P
E
Y
S
V
A
N
D
T
G
F
V
Dog
Lupus familis
XP_855060
289
32919
T201
Y
L
G
R
D
T
D
T
Y
N
Y
K
P
E
C
Cat
Felis silvestris
Mouse
Mus musculus
P06797
334
37529
V219
K
Y
R
A
E
F
A
V
A
N
D
T
G
F
V
Rat
Rattus norvegicus
P07154
334
37642
V219
K
Y
R
A
E
Y
A
V
A
N
D
T
G
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90686
334
37200
D204
N
R
G
I
D
S
E
D
A
Y
P
Y
I
G
Q
Frog
Xenopus laevis
NP_001087489
335
37630
S201
G
G
I
D
S
E
D
S
Y
P
Y
T
A
K
D
Zebra Danio
Brachydanio rerio
NP_997749
337
38399
S203
N
G
L
D
S
E
E
S
Y
P
Y
L
G
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
C251
Y
E
A
I
D
D
S
C
H
F
N
K
G
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65493
355
39599
D223
G
G
L
H
K
E
D
D
Y
P
Y
L
M
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
30
30.4
N.A.
25.7
25.7
N.A.
N.A.
21.2
24.4
25.5
N.A.
22.6
N.A.
N.A.
N.A.
Protein Similarity:
100
46.1
41.1
41.8
N.A.
40.4
40.4
N.A.
N.A.
36.5
40.2
38.8
N.A.
33.4
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
6.6
N.A.
0
0
N.A.
N.A.
0
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
33.3
33.3
N.A.
26.6
26.6
N.A.
N.A.
13.3
26.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
0
0
19
0
46
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
19
28
10
28
19
0
10
37
0
0
0
19
% D
% Glu:
0
10
0
0
28
28
19
0
0
0
0
0
0
19
10
% E
% Phe:
0
10
0
0
0
10
0
0
0
10
0
0
0
37
0
% F
% Gly:
19
28
19
0
0
0
0
0
10
0
0
0
55
10
10
% G
% His:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
19
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
37
0
0
0
28
10
0
0
0
0
0
28
0
10
0
% K
% Leu:
0
10
19
0
0
0
0
0
0
0
0
19
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
19
0
19
0
0
0
0
0
0
46
10
0
0
0
0
% N
% Pro:
10
0
0
19
0
0
0
0
0
28
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
10
19
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
10
37
28
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
0
46
0
19
0
% T
% Val:
0
0
0
0
0
0
0
37
0
0
0
0
10
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
19
37
0
0
0
28
0
0
37
10
37
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _