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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTSL3 All Species: 3.03
Human Site: S168 Identified Species: 6.67
UniProt: Q5NE16 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5NE16 NP_001903 218 25059 S168 A S G E S Q Q S P E V A Q Y S
Chimpanzee Pan troglodytes XP_001137800 299 33813 P210 K A V A T V G P I S V A I D A
Rhesus Macaque Macaca mulatta XP_001086024 333 37445 P244 K A V A T V G P I S V A I D A
Dog Lupus familis XP_855060 289 32919 Q226 S L N G R R L Q Q Q R S R S W
Cat Felis silvestris
Mouse Mus musculus P06797 334 37529 P244 K A V A T V G P I S V A M D A
Rat Rattus norvegicus P07154 334 37642 P244 K A V A T V G P I S V A M D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90686 334 37200 Y229 K A A K C R G Y R E I P E D N
Frog Xenopus laevis NP_001087489 335 37630 F226 N S A N D T G F V D V P S G S
Zebra Danio Brachydanio rerio NP_997749 337 38399 F228 S A A N D T G F V D I P S G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95029 371 41582 M276 P Q G D E K K M A E A V A T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65493 355 39599 Y248 E R V T I S G Y E D V P E N D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.4 30 30.4 N.A. 25.7 25.7 N.A. N.A. 21.2 24.4 25.5 N.A. 22.6 N.A. N.A. N.A.
Protein Similarity: 100 46.1 41.1 41.8 N.A. 40.4 40.4 N.A. N.A. 36.5 40.2 38.8 N.A. 33.4 N.A. N.A. N.A.
P-Site Identity: 100 13.3 13.3 0 N.A. 13.3 13.3 N.A. N.A. 6.6 20 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 33.3 33.3 N.A. 33.3 33.3 N.A. N.A. 46.6 26.6 26.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 34 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 55 28 37 0 0 0 0 10 0 10 46 10 0 37 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 19 0 0 0 0 28 0 0 0 46 10 % D
% Glu: 10 0 0 10 10 0 0 0 10 28 0 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 0 19 10 0 0 73 0 0 0 0 0 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 37 0 19 0 19 0 0 % I
% Lys: 46 0 0 10 0 10 10 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 19 0 0 % M
% Asn: 10 0 10 19 0 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 10 0 0 0 0 0 0 37 10 0 0 37 0 0 0 % P
% Gln: 0 10 0 0 0 10 10 10 10 10 0 0 10 0 0 % Q
% Arg: 0 10 0 0 10 19 0 0 10 0 10 0 10 0 0 % R
% Ser: 19 19 0 0 10 10 0 10 0 37 0 10 19 10 19 % S
% Thr: 0 0 0 10 37 19 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 46 0 0 37 0 0 19 0 64 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 19 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _