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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSL3
All Species:
0.3
Human Site:
S97
Identified Species:
0.67
UniProt:
Q5NE16
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5NE16
NP_001903
218
25059
S97
T
E
K
L
V
S
L
S
V
Q
T
W
W
T
A
Chimpanzee
Pan troglodytes
XP_001137800
299
33813
F118
G
A
L
E
G
Q
M
F
R
K
T
G
R
L
I
Rhesus Macaque
Macaca mulatta
XP_001086024
333
37445
F152
G
A
L
E
G
Q
M
F
R
K
T
G
K
L
V
Dog
Lupus familis
XP_855060
289
32919
F148
G
D
L
K
G
Q
M
F
Q
K
T
G
K
L
N
Cat
Felis silvestris
Mouse
Mus musculus
P06797
334
37529
F152
G
C
L
E
G
Q
M
F
L
K
T
G
K
L
I
Rat
Rattus norvegicus
P07154
334
37642
F152
G
C
L
E
G
Q
M
F
L
K
T
G
K
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90686
334
37200
K158
G
A
L
E
G
Q
L
K
R
R
T
G
K
L
L
Frog
Xenopus laevis
NP_001087489
335
37630
Y152
G
A
L
E
G
Q
H
Y
R
K
A
G
K
L
I
Zebra Danio
Brachydanio rerio
NP_997749
337
38399
F154
G
A
L
E
G
Q
M
F
R
K
T
G
K
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
F192
G
A
L
E
G
Q
H
F
R
K
S
G
V
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65493
355
39599
Q175
A
A
V
E
G
I
N
Q
I
T
T
G
N
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
30
30.4
N.A.
25.7
25.7
N.A.
N.A.
21.2
24.4
25.5
N.A.
22.6
N.A.
N.A.
N.A.
Protein Similarity:
100
46.1
41.1
41.8
N.A.
40.4
40.4
N.A.
N.A.
36.5
40.2
38.8
N.A.
33.4
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
0
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
26.6
N.A.
26.6
26.6
N.A.
N.A.
20
6.6
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
64
0
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
82
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% F
% Gly:
82
0
0
0
91
0
0
0
0
0
0
91
0
0
0
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
37
% I
% Lys:
0
0
10
10
0
0
0
10
0
73
0
0
64
0
0
% K
% Leu:
0
0
82
10
0
0
19
0
19
0
0
0
0
91
10
% L
% Met:
0
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
82
0
10
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
55
10
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
82
0
0
10
0
% T
% Val:
0
0
10
0
10
0
0
0
10
0
0
0
10
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _