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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCEL
All Species:
17.21
Human Site:
Y418
Identified Species:
31.55
UniProt:
Q5QJ74
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5QJ74
NP_001123519.1
424
48195
Y418
I
R
D
G
D
K
I
Y
V
E
S
K
T
K
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107143
424
48146
Y418
I
R
D
G
D
K
I
Y
V
E
S
K
T
K
_
Dog
Lupus familis
XP_546476
474
54071
Y468
I
R
D
G
D
K
I
Y
V
E
S
K
T
K
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5W3
424
48013
F418
I
R
D
G
D
K
I
F
V
E
S
K
T
K
_
Rat
Rattus norvegicus
Q5PQJ7
424
48027
F418
I
R
D
G
D
K
I
F
V
E
S
K
T
K
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505426
448
50738
Y442
I
R
D
G
D
K
I
Y
V
E
P
K
T
K
_
Chicken
Gallus gallus
XP_427094
424
48312
Y418
I
R
D
G
D
K
I
Y
V
E
P
R
M
K
_
Frog
Xenopus laevis
Q5U508
522
58770
E494
S
Y
Q
S
S
K
M
E
G
K
E
I
E
L
E
Zebra Danio
Brachydanio rerio
Q5U378
521
59024
A492
T
Y
T
C
A
K
M
A
D
R
E
I
E
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610562
459
53124
I453
N
I
Q
S
G
D
E
I
I
I
D
A
K
K
_
Honey Bee
Apis mellifera
XP_625182
456
52092
E434
Y
N
I
R
N
G
D
E
I
I
I
D
S
K
L
Nematode Worm
Caenorhab. elegans
Q9BLB6
253
28846
Sea Urchin
Strong. purpuratus
XP_795187
436
49499
I430
Y
K
I
G
D
G
D
I
F
D
I
G
P
A
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
89
N.A.
97.4
96.9
N.A.
89
89.3
24.3
23.2
N.A.
38.5
37.9
20.7
36.4
Protein Similarity:
100
N.A.
99.7
89
N.A.
99.5
99.5
N.A.
92.1
94
42.5
40.6
N.A.
55.7
58.3
35.3
58.2
P-Site Identity:
100
N.A.
100
100
N.A.
92.8
92.8
N.A.
92.8
78.5
6.6
6.6
N.A.
7.1
6.6
0
14.2
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
92.8
85.7
20
13.3
N.A.
14.2
26.6
0
28.5
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
0
62
8
16
0
8
8
8
8
0
0
8
% D
% Glu:
0
0
0
0
0
0
8
16
0
54
16
0
16
0
8
% E
% Phe:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
62
8
16
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
54
8
16
0
0
0
54
16
16
16
16
16
0
8
0
% I
% Lys:
0
8
0
0
0
70
0
0
0
8
0
47
8
70
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
0
% P
% Gln:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
54
0
8
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
0
0
16
8
0
0
0
0
0
39
0
8
0
0
% S
% Thr:
8
0
8
0
0
0
0
0
0
0
0
0
47
0
0
% T
% Val:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
16
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% _