KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNTTIP2
All Species:
11.82
Human Site:
S512
Identified Species:
37.14
UniProt:
Q5QJE6
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5QJE6
NP_055412.2
756
84469
S512
L
E
E
E
D
K
A
S
E
V
A
I
E
E
E
Chimpanzee
Pan troglodytes
XP_513572
1102
123138
S858
L
E
E
E
D
K
A
S
E
V
A
I
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001103381
752
85192
S518
L
E
E
E
D
K
A
S
E
V
A
T
E
E
E
Dog
Lupus familis
XP_547275
770
87068
D517
T
T
P
G
L
S
T
D
K
H
F
Y
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2M2
758
84259
S512
Y
L
E
D
K
A
P
S
E
V
A
I
E
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511161
310
35197
R85
G
K
A
G
I
N
A
R
L
T
E
L
A
C
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139258
941
103483
L633
A
Q
K
E
M
I
S
L
L
D
S
S
D
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791185
326
37310
D101
D
E
Q
D
D
D
S
D
A
S
I
D
S
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
77.2
72.5
N.A.
59.8
N.A.
N.A.
28.5
N.A.
N.A.
29.1
N.A.
N.A.
N.A.
N.A.
25.5
Protein Similarity:
100
68.5
82.2
82.5
N.A.
72.4
N.A.
N.A.
36.1
N.A.
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
34.5
P-Site Identity:
100
100
93.3
6.6
N.A.
60
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
20
N.A.
66.6
N.A.
N.A.
20
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
0
0
13
50
0
13
0
50
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
13
0
0
25
50
13
0
25
0
13
0
13
13
13
0
% D
% Glu:
0
50
50
50
0
0
0
0
50
0
13
0
50
63
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
13
0
% F
% Gly:
13
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
13
0
0
0
0
13
38
0
0
0
% I
% Lys:
0
13
13
0
13
38
0
0
13
0
0
0
0
0
0
% K
% Leu:
38
13
0
0
13
0
0
13
25
0
0
13
13
0
0
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
13
% P
% Gln:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
13
25
50
0
13
13
13
13
0
0
% S
% Thr:
13
13
0
0
0
0
13
0
0
13
0
13
0
0
13
% T
% Val:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _