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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACER2 All Species: 20.3
Human Site: S15 Identified Species: 40.61
UniProt: Q5QJU3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5QJU3 NP_001010887.2 275 31309 S15 D Q L Q A G S S E V D W C E D
Chimpanzee Pan troglodytes XP_001150335 226 25705
Rhesus Macaque Macaca mulatta XP_001101088 185 21029
Dog Lupus familis XP_538674 275 31336 S15 D Q L R A G S S E V D W C E D
Cat Felis silvestris
Mouse Mus musculus Q8VD53 275 31351 S15 D H L R A G S S E V D W C E D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519806 288 32106 L12 T S H R S W V L I P A L R D V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q568I2 266 30890 S10 G V F S Y E S S E V D W C E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIP7 283 32774 S25 E H L R P G S S P V D W C E G
Honey Bee Apis mellifera XP_623814 269 30990 S10 K P F E A G S S P I D W C E R
Nematode Worm Caenorhab. elegans O45145 272 31143 H16 W F E Y E S G H A W C E S A Y
Sea Urchin Strong. purpuratus XP_799207 298 34491 A40 D N L E R G S A A I D W C E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02896 317 37212 S21 G Y W G K P T S L I D W C E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 65.8 94.1 N.A. 93 N.A. N.A. 52.4 N.A. N.A. 42.9 N.A. 47.3 47.6 28.7 45.3
Protein Similarity: 100 82.1 66.9 97.8 N.A. 98.1 N.A. N.A. 64.2 N.A. N.A. 60.3 N.A. 65.7 65.4 50.5 65.1
P-Site Identity: 100 0 0 93.3 N.A. 86.6 N.A. N.A. 0 N.A. N.A. 60 N.A. 60 53.3 0 53.3
P-Site Similarity: 100 0 0 100 N.A. 93.3 N.A. N.A. 20 N.A. N.A. 60 N.A. 73.3 66.6 0 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 0 0 9 17 0 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 67 0 0 % C
% Asp: 34 0 0 0 0 0 0 0 0 0 67 0 0 9 34 % D
% Glu: 9 0 9 17 9 9 0 0 34 0 0 9 0 67 9 % E
% Phe: 0 9 17 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 9 0 50 9 0 0 0 0 0 0 0 9 % G
% His: 0 17 9 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 25 0 0 0 0 0 % I
% Lys: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 42 0 0 0 0 9 9 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 9 0 0 9 9 0 0 17 9 0 0 0 0 0 % P
% Gln: 0 17 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 34 9 0 0 0 0 0 0 0 9 0 9 % R
% Ser: 0 9 0 9 9 9 59 59 0 0 0 0 9 0 0 % S
% Thr: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 9 0 0 42 0 0 0 0 9 % V
% Trp: 9 0 9 0 0 9 0 0 0 9 0 67 0 0 0 % W
% Tyr: 0 9 0 9 9 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _