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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACER2 All Species: 13.64
Human Site: S236 Identified Species: 27.27
UniProt: Q5QJU3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5QJU3 NP_001010887.2 275 31309 S236 F A Y F D A A S E I P E Q G P
Chimpanzee Pan troglodytes XP_001150335 226 25705 K197 P E Q G P V I K F W P N E K W
Rhesus Macaque Macaca mulatta XP_001101088 185 21029 K156 P E Q G P V I K F W P S E K W
Dog Lupus familis XP_538674 275 31336 S236 F A Y F D A A S E I P E Q G P
Cat Felis silvestris
Mouse Mus musculus Q8VD53 275 31351 S236 F A Y F D A A S E I P E Q G P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519806 288 32106 A230 W S L P S L T A S A D R R R G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q568I2 266 30890 Q230 I A Y L D A S Q E I P Y S L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIP7 283 32774 S246 F A Y F Y V E S E L P Q R Q P
Honey Bee Apis mellifera XP_623814 269 30990 E231 F A Y F S V K E E K P Q Q S P
Nematode Worm Caenorhab. elegans O45145 272 31143 S238 F S M I D I E S R T K T H K Y
Sea Urchin Strong. purpuratus XP_799207 298 34491 N261 F A Y F D A M N E C P E M G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02896 317 37212 V256 G T G V Y I F V V Y L Q Y L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 65.8 94.1 N.A. 93 N.A. N.A. 52.4 N.A. N.A. 42.9 N.A. 47.3 47.6 28.7 45.3
Protein Similarity: 100 82.1 66.9 97.8 N.A. 98.1 N.A. N.A. 64.2 N.A. N.A. 60.3 N.A. 65.7 65.4 50.5 65.1
P-Site Identity: 100 6.6 6.6 100 N.A. 100 N.A. N.A. 0 N.A. N.A. 53.3 N.A. 53.3 53.3 20 73.3
P-Site Similarity: 100 13.3 13.3 100 N.A. 100 N.A. N.A. 26.6 N.A. N.A. 60 N.A. 73.3 60 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 59 0 0 0 42 25 9 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 17 0 0 0 0 17 9 59 0 0 34 17 0 0 % E
% Phe: 59 0 0 50 0 0 9 0 17 0 0 0 0 0 0 % F
% Gly: 9 0 9 17 0 0 0 0 0 0 0 0 0 34 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 9 0 17 17 0 0 34 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 17 0 9 9 0 0 25 0 % K
% Leu: 0 0 9 9 0 9 0 0 0 9 9 0 0 17 0 % L
% Met: 0 0 9 0 0 0 9 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % N
% Pro: 17 0 0 9 17 0 0 0 0 0 75 0 0 0 59 % P
% Gln: 0 0 17 0 0 0 0 9 0 0 0 25 34 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 0 9 17 9 9 % R
% Ser: 0 17 0 0 17 0 9 42 9 0 0 9 9 9 0 % S
% Thr: 0 9 0 0 0 0 9 0 0 9 0 9 0 0 0 % T
% Val: 0 0 0 9 0 34 0 9 9 0 0 0 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 17 0 0 0 0 17 % W
% Tyr: 0 0 59 0 17 0 0 0 0 9 0 9 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _