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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACER2 All Species: 23.03
Human Site: Y113 Identified Species: 46.06
UniProt: Q5QJU3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5QJU3 NP_001010887.2 275 31309 Y113 A M W F P R R Y L P K I F R N
Chimpanzee Pan troglodytes XP_001150335 226 25705 L83 F K V V V S V L S A V T T C L
Rhesus Macaque Macaca mulatta XP_001101088 185 21029 L42 F K V V V C V L S A V T T C L
Dog Lupus familis XP_538674 275 31336 Y113 A M W F P R R Y L P K V F R N
Cat Felis silvestris
Mouse Mus musculus Q8VD53 275 31351 Y113 A M W F P R R Y L P K I F R N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519806 288 32106 Y99 A M W F P R R Y L P R V F R N
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q568I2 266 30890 H108 S L W F P R K H F P S F V K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIP7 283 32774 Y123 S L F Y P K R Y Y P K F V K N
Honey Bee Apis mellifera XP_623814 269 30990 Y108 C M F L P R R Y F P N I L H N
Nematode Worm Caenorhab. elegans O45145 272 31143 W115 V Y I P V M K W F P E K F S K
Sea Urchin Strong. purpuratus XP_799207 298 34491 Y138 A L W Y P R R Y Y P A N I K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02896 317 37212 E118 S I F A E T Q E I L I K D E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 65.8 94.1 N.A. 93 N.A. N.A. 52.4 N.A. N.A. 42.9 N.A. 47.3 47.6 28.7 45.3
Protein Similarity: 100 82.1 66.9 97.8 N.A. 98.1 N.A. N.A. 64.2 N.A. N.A. 60.3 N.A. 65.7 65.4 50.5 65.1
P-Site Identity: 100 0 0 93.3 N.A. 100 N.A. N.A. 86.6 N.A. N.A. 33.3 N.A. 40 53.3 13.3 46.6
P-Site Similarity: 100 0 0 100 N.A. 100 N.A. N.A. 100 N.A. N.A. 73.3 N.A. 80 60 33.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 0 9 0 0 0 0 0 17 9 0 0 0 0 % A
% Cys: 9 0 0 0 0 9 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % D
% Glu: 0 0 0 0 9 0 0 9 0 0 9 0 0 9 0 % E
% Phe: 17 0 25 42 0 0 0 0 25 0 0 17 42 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % H
% Ile: 0 9 9 0 0 0 0 0 9 0 9 25 9 0 0 % I
% Lys: 0 17 0 0 0 9 17 0 0 0 34 17 0 25 17 % K
% Leu: 0 25 0 9 0 0 0 17 34 9 0 0 9 0 17 % L
% Met: 0 42 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 50 % N
% Pro: 0 0 0 9 67 0 0 0 0 75 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 59 59 0 0 0 9 0 0 34 0 % R
% Ser: 25 0 0 0 0 9 0 0 17 0 9 0 0 9 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 17 17 0 0 % T
% Val: 9 0 17 17 25 0 17 0 0 0 17 17 17 0 0 % V
% Trp: 0 0 50 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 17 0 0 0 59 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _