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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC6
All Species:
20.61
Human Site:
S236
Identified Species:
37.78
UniProt:
Q5RKV6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5RKV6
NP_478126.1
272
28235
S236
G
E
G
G
L
T
E
S
W
A
E
A
V
R
L
Chimpanzee
Pan troglodytes
XP_523406
272
28247
S236
G
E
G
G
L
T
E
S
W
A
E
A
V
R
L
Rhesus Macaque
Macaca mulatta
XP_001101736
185
19058
G157
W
A
E
A
V
R
L
G
L
E
G
C
Q
R
L
Dog
Lupus familis
XP_546833
272
28271
S236
G
E
G
G
P
P
E
S
W
A
E
A
V
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW3
273
28352
S237
G
E
G
G
Q
T
E
S
W
T
D
A
V
R
L
Rat
Rattus norvegicus
XP_226471
312
32781
S276
G
E
G
G
Q
T
E
S
W
T
D
A
V
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
T235
D
G
E
M
R
E
D
T
L
T
E
A
M
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609618
246
27003
A214
L
E
T
V
I
E
T
A
M
A
G
C
R
E
I
Honey Bee
Apis mellifera
XP_623498
273
30513
T239
F
L
I
G
S
I
D
T
N
S
I
I
Q
A
T
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
T207
L
H
I
D
H
L
S
T
V
M
D
A
A
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328307
263
28041
A235
S
T
A
N
L
N
E
A
M
Q
L
C
L
D
A
Maize
Zea mays
NP_001168912
209
22466
A181
S
D
G
R
I
T
N
A
V
E
L
C
M
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46948
246
27542
G217
L
E
N
V
L
A
I
G
I
A
G
A
H
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
66.5
95.2
N.A.
91.5
80.4
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
30.8
35.9
26.1
N.A.
Protein Similarity:
100
99.6
66.5
95.5
N.A.
94.5
82.6
N.A.
N.A.
N.A.
N.A.
66.9
N.A.
46.6
56.7
42.2
N.A.
P-Site Identity:
100
100
13.3
86.6
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
20
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
33.3
26.6
26.6
N.A.
Percent
Protein Identity:
26.8
28.3
N.A.
N.A.
23.5
N.A.
Protein Similarity:
43.3
42.6
N.A.
N.A.
40.4
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
26.6
40
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
0
24
0
39
0
62
8
8
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
0
% C
% Asp:
8
8
0
8
0
0
16
0
0
0
24
0
0
16
0
% D
% Glu:
0
54
16
0
0
16
47
0
0
16
31
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
39
8
47
47
0
0
0
16
0
0
24
0
0
0
0
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
16
0
16
8
8
0
8
0
8
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
24
8
0
0
31
8
8
0
16
0
16
0
8
0
47
% L
% Met:
0
0
0
8
0
0
0
0
16
8
0
0
16
0
0
% M
% Asn:
0
0
8
8
0
8
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
8
0
0
16
0
0
% Q
% Arg:
0
0
0
8
8
8
0
0
0
0
0
0
8
62
0
% R
% Ser:
16
0
0
0
8
0
8
39
0
8
0
0
0
0
0
% S
% Thr:
0
8
8
0
0
39
8
24
0
24
0
0
0
0
16
% T
% Val:
0
0
0
16
8
0
0
0
16
0
0
0
39
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
39
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _