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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1L
All Species:
26.06
Human Site:
T85
Identified Species:
52.12
UniProt:
Q5SGD2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SGD2
NP_640338.2
360
41053
T85
L
E
A
E
F
S
K
T
W
E
F
K
N
H
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096883
233
26345
Dog
Lupus familis
XP_850909
360
41007
T85
L
E
A
E
F
S
K
T
W
E
F
K
S
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHN0
360
41031
T85
L
E
A
E
F
S
K
T
W
E
F
K
S
H
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508742
243
27525
Chicken
Gallus gallus
XP_426717
360
41054
T85
L
D
A
E
F
S
K
T
W
E
F
K
S
H
N
Frog
Xenopus laevis
NP_001116353
360
41086
T85
L
E
A
E
F
S
K
T
W
E
Y
K
S
N
N
Zebra Danio
Brachydanio rerio
NP_001071068
361
40676
T85
L
D
A
E
F
S
K
T
W
E
F
K
N
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609154
524
57993
S103
A
S
A
G
D
H
Q
S
W
E
E
M
K
Q
Q
Honey Bee
Apis mellifera
XP_624449
483
54283
S113
V
N
N
G
V
K
L
S
W
E
L
K
Q
G
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791681
256
28301
Poplar Tree
Populus trichocarpa
XP_002318384
308
33920
E43
G
W
K
S
E
E
G
E
L
S
C
G
Y
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
64.7
99.7
N.A.
99.1
N.A.
N.A.
56.3
97.5
91.9
87.5
N.A.
32.2
39.5
N.A.
41.1
Protein Similarity:
100
N.A.
64.7
100
N.A.
99.7
N.A.
N.A.
61.3
99.4
98
95.2
N.A.
48
51.9
N.A.
55.5
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
N.A.
N.A.
0
86.6
80
86.6
N.A.
20
20
N.A.
0
P-Site Similarity:
100
N.A.
0
100
N.A.
100
N.A.
N.A.
0
100
100
100
N.A.
33.3
40
N.A.
0
Percent
Protein Identity:
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
17
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
34
0
50
9
9
0
9
0
67
9
0
0
0
0
% E
% Phe:
0
0
0
0
50
0
0
0
0
0
42
0
0
0
0
% F
% Gly:
9
0
0
17
0
0
9
0
0
0
0
9
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
34
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
9
50
0
0
0
0
59
9
0
0
% K
% Leu:
50
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
0
0
17
17
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
9
0
50
0
17
0
9
0
0
34
9
9
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
67
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _