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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1L
All Species:
20.91
Human Site:
Y188
Identified Species:
41.82
UniProt:
Q5SGD2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SGD2
NP_640338.2
360
41053
Y188
L
E
K
L
T
V
S
Y
D
E
A
G
T
T
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096883
233
26345
I70
E
A
G
T
T
C
L
I
A
L
L
S
D
K
D
Dog
Lupus familis
XP_850909
360
41007
Y188
L
E
K
L
T
V
S
Y
D
E
A
G
T
T
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHN0
360
41031
Y188
L
E
K
L
T
V
S
Y
D
E
A
G
T
T
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508742
243
27525
L80
E
A
G
I
S
S
V
L
A
I
L
K
F
K
D
Chicken
Gallus gallus
XP_426717
360
41054
Y188
L
E
K
L
T
V
S
Y
D
E
A
G
T
T
C
Frog
Xenopus laevis
NP_001116353
360
41086
Y188
L
E
K
L
S
V
S
Y
D
E
A
G
T
T
C
Zebra Danio
Brachydanio rerio
NP_001071068
361
40676
H188
V
E
K
F
S
A
S
H
D
E
A
G
T
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609154
524
57993
T319
V
E
Q
A
K
R
A
T
N
I
A
G
T
T
A
Honey Bee
Apis mellifera
XP_624449
483
54283
M306
V
E
A
A
K
K
N
M
D
I
A
G
T
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791681
256
28301
L93
G
S
T
A
L
V
A
L
I
T
E
S
D
V
I
Poplar Tree
Populus trichocarpa
XP_002318384
308
33920
L145
S
T
A
S
T
A
V
L
V
G
D
H
L
Y
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
64.7
99.7
N.A.
99.1
N.A.
N.A.
56.3
97.5
91.9
87.5
N.A.
32.2
39.5
N.A.
41.1
Protein Similarity:
100
N.A.
64.7
100
N.A.
99.7
N.A.
N.A.
61.3
99.4
98
95.2
N.A.
48
51.9
N.A.
55.5
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
N.A.
N.A.
0
100
93.3
66.6
N.A.
33.3
40
N.A.
6.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
N.A.
N.A.
13.3
100
100
86.6
N.A.
60
53.3
N.A.
13.3
Percent
Protein Identity:
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
17
25
0
17
17
0
17
0
67
0
0
0
17
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
50
% C
% Asp:
0
0
0
0
0
0
0
0
59
0
9
0
17
0
17
% D
% Glu:
17
67
0
0
0
0
0
0
0
50
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
17
0
0
0
0
0
0
9
0
67
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
9
25
0
0
0
0
9
% I
% Lys:
0
0
50
0
17
9
0
0
0
0
0
9
0
17
0
% K
% Leu:
42
0
0
42
9
0
9
25
0
9
17
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
9
25
9
50
0
0
0
0
17
0
0
0
% S
% Thr:
0
9
9
9
50
0
0
9
0
9
0
0
67
67
0
% T
% Val:
25
0
0
0
0
50
17
0
9
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _