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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1L
All Species:
30.3
Human Site:
Y270
Identified Species:
60.61
UniProt:
Q5SGD2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SGD2
NP_640338.2
360
41053
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096883
233
26345
V151
P
L
K
N
L
N
V
V
I
P
D
P
D
I
L
Dog
Lupus familis
XP_850909
360
41007
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHN0
360
41031
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508742
243
27525
V161
P
L
K
N
L
N
V
V
I
P
D
P
D
I
L
Chicken
Gallus gallus
XP_426717
360
41054
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Frog
Xenopus laevis
NP_001116353
360
41086
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Zebra Danio
Brachydanio rerio
NP_001071068
361
40676
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609154
524
57993
Y401
T
S
R
A
L
G
D
Y
P
L
K
D
K
N
L
Honey Bee
Apis mellifera
XP_624449
483
54283
Y388
T
S
R
A
L
G
D
Y
P
L
K
D
K
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791681
256
28301
A174
K
D
H
K
F
V
V
A
D
P
D
I
L
S
F
Poplar Tree
Populus trichocarpa
XP_002318384
308
33920
I226
F
V
V
A
E
P
E
I
Q
E
Q
K
I
D
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
64.7
99.7
N.A.
99.1
N.A.
N.A.
56.3
97.5
91.9
87.5
N.A.
32.2
39.5
N.A.
41.1
Protein Similarity:
100
N.A.
64.7
100
N.A.
99.7
N.A.
N.A.
61.3
99.4
98
95.2
N.A.
48
51.9
N.A.
55.5
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
N.A.
N.A.
6.6
100
100
100
N.A.
66.6
60
N.A.
6.6
P-Site Similarity:
100
N.A.
26.6
100
N.A.
100
N.A.
N.A.
26.6
100
100
100
N.A.
86.6
80
N.A.
13.3
Percent
Protein Identity:
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
67
0
9
0
25
17
17
9
0
% D
% Glu:
0
0
0
0
9
0
9
0
0
9
0
0
0
0
9
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
17
0
0
9
9
17
0
% I
% Lys:
9
0
17
9
0
0
0
0
0
0
67
9
17
9
0
% K
% Leu:
0
17
0
0
84
0
0
0
0
67
0
0
59
0
34
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
17
0
0
0
0
0
50
0
59
0
% N
% Pro:
17
0
0
0
0
9
0
0
67
25
0
17
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% Q
% Arg:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
67
0
50
0
0
0
0
0
0
0
0
0
9
0
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
9
0
0
9
25
17
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _