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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIATL1
All Species:
26.67
Human Site:
S229
Identified Species:
48.89
UniProt:
Q5SR56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SR56
NP_115947.2
506
54545
S229
P
E
K
M
R
P
V
S
W
G
A
Q
I
S
W
Chimpanzee
Pan troglodytes
XP_520704
440
47541
A173
A
Q
I
S
W
K
Q
A
D
P
F
A
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001104588
506
54465
S229
P
E
K
M
R
P
V
S
W
G
A
Q
I
S
W
Dog
Lupus familis
XP_533564
515
55621
S229
S
E
K
M
R
P
L
S
W
G
A
K
I
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIA9
507
55084
S231
S
E
K
I
R
P
A
S
W
G
A
Q
I
S
W
Rat
Rattus norvegicus
B2RYH9
507
54917
S231
P
E
K
I
R
P
A
S
W
G
A
Q
I
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512475
466
50593
P200
R
P
A
S
W
G
A
P
I
S
W
E
Q
A
D
Chicken
Gallus gallus
NP_001034410
492
52978
S221
P
E
E
M
R
P
V
S
W
G
A
P
I
S
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663499
486
52565
W220
D
K
M
R
L
N
T
W
G
A
P
I
S
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728811
680
72850
S412
S
E
K
M
R
P
A
S
W
G
A
P
I
S
W
Honey Bee
Apis mellifera
XP_624637
518
55806
K238
A
Y
L
G
K
V
G
K
D
H
T
I
L
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780651
530
56878
L249
L
L
C
I
A
V
F
L
S
Y
L
P
E
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04301
562
62621
S293
P
F
E
L
L
T
R
S
F
C
L
S
S
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
99.4
91.6
N.A.
89.7
89.7
N.A.
66.2
70.5
N.A.
67.9
N.A.
43.5
55.5
N.A.
54.9
Protein Similarity:
100
86.9
99.8
94.3
N.A.
93.2
93.4
N.A.
76
81.2
N.A.
78.8
N.A.
55.5
72.7
N.A.
69.2
P-Site Identity:
100
0
100
80
N.A.
80
86.6
N.A.
0
86.6
N.A.
0
N.A.
80
0
N.A.
0
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
93.3
N.A.
13.3
93.3
N.A.
6.6
N.A.
80
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
8
0
31
8
0
8
54
8
0
24
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
16
0
0
0
0
0
8
% D
% Glu:
0
54
16
0
0
0
0
0
0
0
0
8
8
0
8
% E
% Phe:
0
8
0
0
0
0
8
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
8
0
8
54
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
24
0
0
0
0
8
0
0
16
54
0
0
% I
% Lys:
0
8
47
0
8
8
0
8
0
0
0
8
0
0
8
% K
% Leu:
8
8
8
8
16
0
8
8
0
0
16
0
8
8
8
% L
% Met:
0
0
8
39
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
39
8
0
0
0
54
0
8
0
8
8
24
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
31
8
0
0
% Q
% Arg:
8
0
0
8
54
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
24
0
0
16
0
0
0
62
8
8
0
8
24
54
0
% S
% Thr:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
16
24
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
16
0
0
8
54
0
8
0
0
8
54
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _