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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIATL1 All Species: 23.33
Human Site: S468 Identified Species: 42.78
UniProt: Q5SR56 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SR56 NP_115947.2 506 54545 S468 H S N S S S G S L T N T P E R
Chimpanzee Pan troglodytes XP_520704 440 47541 S402 H N N S S S G S L T N T P E R
Rhesus Macaque Macaca mulatta XP_001104588 506 54465 S468 H S N S S S G S L T N T P E R
Dog Lupus familis XP_533564 515 55621 S477 H S N S I S G S L I N T P E R
Cat Felis silvestris
Mouse Mus musculus Q8CIA9 507 55084 S470 H N N S T S G S L S T P P E R
Rat Rattus norvegicus B2RYH9 507 54917 S470 H N N S I S G S L S T P P E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512475 466 50593 L429 F I P E H T N L N V R S G N W
Chicken Gallus gallus NP_001034410 492 52978 L454 L F I P E H N L T L R S G S H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663499 486 52565 P449 F I P D H S T P P S T P C Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728811 680 72850 T642 A F I P E G Q T S T L E K K R
Honey Bee Apis mellifera XP_624637 518 55806 R474 H H P S T S R R P S G K Y A Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780651 530 56878 S492 P S A A P P Q S P S L K L V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04301 562 62621 I522 P T D I F V R I L D V Y K K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 99.4 91.6 N.A. 89.7 89.7 N.A. 66.2 70.5 N.A. 67.9 N.A. 43.5 55.5 N.A. 54.9
Protein Similarity: 100 86.9 99.8 94.3 N.A. 93.2 93.4 N.A. 76 81.2 N.A. 78.8 N.A. 55.5 72.7 N.A. 69.2
P-Site Identity: 100 93.3 100 86.6 N.A. 66.6 66.6 N.A. 0 0 N.A. 6.6 N.A. 13.3 20 N.A. 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 80 N.A. 13.3 6.6 N.A. 20 N.A. 26.6 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 8 16 0 0 0 0 0 0 8 0 47 0 % E
% Phe: 16 16 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 47 0 0 0 8 0 16 0 0 % G
% His: 54 8 0 0 16 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 16 16 8 16 0 0 8 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 16 16 16 8 % K
% Leu: 8 0 0 0 0 0 0 16 54 8 16 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 24 47 0 0 0 16 0 8 0 31 0 0 8 0 % N
% Pro: 16 0 24 16 8 8 0 8 24 0 0 24 47 0 0 % P
% Gln: 0 0 0 0 0 0 16 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 16 8 0 0 16 0 0 0 54 % R
% Ser: 0 31 0 54 24 62 0 54 8 39 0 16 0 8 0 % S
% Thr: 0 8 0 0 16 8 8 8 8 31 24 31 0 0 8 % T
% Val: 0 0 0 0 0 8 0 0 0 8 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _