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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIATL1
All Species:
19.09
Human Site:
S488
Identified Species:
35
UniProt:
Q5SR56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SR56
NP_115947.2
506
54545
S488
I
E
P
L
L
Q
D
S
S
I
W
E
L
S
S
Chimpanzee
Pan troglodytes
XP_520704
440
47541
S422
I
E
P
L
L
Q
D
S
S
I
W
E
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001104588
506
54465
S488
I
E
P
L
L
Q
D
S
S
I
W
E
L
S
S
Dog
Lupus familis
XP_533564
515
55621
N497
I
E
P
L
L
Q
D
N
S
I
W
E
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIA9
507
55084
S490
I
E
P
L
L
Q
D
S
S
I
W
E
L
S
F
Rat
Rattus norvegicus
B2RYH9
507
54917
S490
I
E
P
L
L
Q
D
S
N
I
W
E
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512475
466
50593
S449
G
S
H
G
H
P
H
S
P
Q
A
P
G
E
A
Chicken
Gallus gallus
NP_001034410
492
52978
S474
G
A
Q
T
H
T
H
S
P
Q
A
G
A
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663499
486
52565
P469
A
G
A
H
T
N
T
P
L
P
G
S
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728811
680
72850
H662
Q
Y
E
I
E
P
G
H
K
A
P
S
S
L
A
Honey Bee
Apis mellifera
XP_624637
518
55806
D494
L
D
V
H
Y
E
G
D
K
L
G
S
G
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780651
530
56878
L512
D
D
V
S
V
P
L
L
T
D
V
D
S
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04301
562
62621
A542
I
P
N
I
A
L
A
A
V
G
I
V
L
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
99.4
91.6
N.A.
89.7
89.7
N.A.
66.2
70.5
N.A.
67.9
N.A.
43.5
55.5
N.A.
54.9
Protein Similarity:
100
86.9
99.8
94.3
N.A.
93.2
93.4
N.A.
76
81.2
N.A.
78.8
N.A.
55.5
72.7
N.A.
69.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
13.3
N.A.
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
13.3
N.A.
0
N.A.
13.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
8
0
8
8
0
8
16
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
0
0
47
8
0
8
0
8
8
0
16
% D
% Glu:
0
47
8
0
8
8
0
0
0
0
0
47
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
16
8
0
8
0
0
16
0
0
8
16
8
16
0
16
% G
% His:
0
0
8
16
16
0
16
8
0
0
0
0
0
0
0
% H
% Ile:
54
0
0
16
0
0
0
0
0
47
8
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
16
0
0
0
0
8
0
% K
% Leu:
8
0
0
47
47
8
8
8
8
8
0
0
54
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
8
47
0
0
24
0
8
16
8
8
8
0
0
0
% P
% Gln:
8
0
8
0
0
47
0
0
0
16
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
54
39
0
0
24
16
62
39
% S
% Thr:
0
0
0
8
8
8
8
0
8
0
0
0
0
0
0
% T
% Val:
0
0
16
0
8
0
0
0
8
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _