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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIATL1
All Species:
21.52
Human Site:
T166
Identified Species:
39.44
UniProt:
Q5SR56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SR56
NP_115947.2
506
54545
T166
T
Q
E
H
E
R
S
T
A
Y
G
W
V
S
A
Chimpanzee
Pan troglodytes
XP_520704
440
47541
S112
V
S
A
T
F
A
A
S
L
V
S
S
P
A
I
Rhesus Macaque
Macaca mulatta
XP_001104588
506
54465
T166
T
Q
E
H
E
R
S
T
A
Y
G
W
V
S
A
Dog
Lupus familis
XP_533564
515
55621
T166
T
Q
E
H
E
R
S
T
A
Y
G
W
V
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIA9
507
55084
T168
T
Q
E
H
E
R
S
T
A
Y
G
W
V
S
A
Rat
Rattus norvegicus
B2RYH9
507
54917
T168
T
Q
E
H
E
R
S
T
A
Y
G
W
V
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512475
466
50593
S139
S
M
A
Y
G
L
V
S
A
T
F
A
A
S
L
Chicken
Gallus gallus
NP_001034410
492
52978
Y160
E
H
E
R
S
T
A
Y
G
L
V
S
A
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663499
486
52565
G159
R
E
R
S
T
A
Y
G
L
V
S
A
T
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728811
680
72850
K349
T
T
P
E
E
R
S
K
A
Y
G
L
A
S
A
Honey Bee
Apis mellifera
XP_624637
518
55806
V171
A
T
F
A
A
S
M
V
I
S
P
A
L
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780651
530
56878
I166
A
T
F
A
A
S
L
I
T
S
P
A
L
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04301
562
62621
K228
M
K
E
R
Y
T
L
K
N
L
S
R
I
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
99.4
91.6
N.A.
89.7
89.7
N.A.
66.2
70.5
N.A.
67.9
N.A.
43.5
55.5
N.A.
54.9
Protein Similarity:
100
86.9
99.8
94.3
N.A.
93.2
93.4
N.A.
76
81.2
N.A.
78.8
N.A.
55.5
72.7
N.A.
69.2
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
13.3
6.6
N.A.
6.6
N.A.
60
0
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
33.3
20
N.A.
13.3
N.A.
60
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
16
16
16
16
0
54
0
0
31
24
8
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
8
8
54
8
47
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
16
0
8
0
0
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
0
0
8
0
0
8
8
0
47
0
0
16
0
% G
% His:
0
8
0
39
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
16
% I
% Lys:
0
8
0
0
0
0
0
16
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
16
0
16
16
0
8
16
0
8
% L
% Met:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
16
0
8
0
0
% P
% Gln:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
16
0
47
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
8
0
8
8
16
47
16
0
16
24
16
0
54
0
% S
% Thr:
47
24
0
8
8
16
0
39
8
8
0
0
8
8
0
% T
% Val:
8
0
0
0
0
0
8
8
0
16
8
0
39
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
8
0
47
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _