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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIATL1 All Species: 23.33
Human Site: Y168 Identified Species: 42.78
UniProt: Q5SR56 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SR56 NP_115947.2 506 54545 Y168 E H E R S T A Y G W V S A T F
Chimpanzee Pan troglodytes XP_520704 440 47541 V114 A T F A A S L V S S P A I G A
Rhesus Macaque Macaca mulatta XP_001104588 506 54465 Y168 E H E R S T A Y G W V S A T F
Dog Lupus familis XP_533564 515 55621 Y168 E H E R S T A Y G W V S A T F
Cat Felis silvestris
Mouse Mus musculus Q8CIA9 507 55084 Y170 E H E R S T A Y G W V S A T F
Rat Rattus norvegicus B2RYH9 507 54917 Y170 E H E R S T A Y G W V S A T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512475 466 50593 T141 A Y G L V S A T F A A S L V T
Chicken Gallus gallus NP_001034410 492 52978 L162 E R S T A Y G L V S A T F A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663499 486 52565 V161 R S T A Y G L V S A T F A A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728811 680 72850 Y351 P E E R S K A Y G L A S A T F
Honey Bee Apis mellifera XP_624637 518 55806 S173 F A A S M V I S P A L G D Y I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780651 530 56878 S168 F A A S L I T S P A L G A Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04301 562 62621 L230 E R Y T L K N L S R I D I F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 99.4 91.6 N.A. 89.7 89.7 N.A. 66.2 70.5 N.A. 67.9 N.A. 43.5 55.5 N.A. 54.9
Protein Similarity: 100 86.9 99.8 94.3 N.A. 93.2 93.4 N.A. 76 81.2 N.A. 78.8 N.A. 55.5 72.7 N.A. 69.2
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 13.3 6.6 N.A. 6.6 N.A. 66.6 0 N.A. 6.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 26.6 20 N.A. 6.6 N.A. 66.6 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 16 16 16 0 54 0 0 31 24 8 62 16 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % D
% Glu: 54 8 47 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 16 0 8 0 0 0 0 0 8 0 0 8 8 8 47 % F
% Gly: 0 0 8 0 0 8 8 0 47 0 0 16 0 8 8 % G
% His: 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 8 0 16 0 8 % I
% Lys: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 16 0 16 16 0 8 16 0 8 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 16 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 16 0 47 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 8 8 16 47 16 0 16 24 16 0 54 0 0 8 % S
% Thr: 0 8 8 16 0 39 8 8 0 0 8 8 0 47 8 % T
% Val: 0 0 0 0 8 8 0 16 8 0 39 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 % W
% Tyr: 0 8 8 0 8 8 0 47 0 0 0 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _