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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGAP8
All Species:
1.21
Human Site:
T346
Identified Species:
2.96
UniProt:
Q5SRD3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SRD3
NP_001071154.1
663
73068
T346
G
L
S
K
D
M
D
T
G
L
G
D
S
I
C
Chimpanzee
Pan troglodytes
XP_001141446
439
48772
I128
D
T
G
L
G
D
S
I
C
F
S
P
S
I
S
Rhesus Macaque
Macaca mulatta
XP_001082744
804
89081
P461
S
I
S
S
T
T
S
P
K
L
D
P
P
P
S
Dog
Lupus familis
XP_848466
936
102470
P593
S
I
S
S
T
T
S
P
K
L
D
P
P
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXK8
857
94393
P514
S
I
S
S
S
T
S
P
K
L
D
P
P
P
S
Rat
Rattus norvegicus
Q8CGU4
1186
124419
K830
M
V
K
K
Q
R
R
K
K
L
S
T
P
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRL1
864
95088
P517
S
I
S
S
T
T
S
P
K
L
D
P
P
P
S
Zebra Danio
Brachydanio rerio
Q08CI4
339
38765
Y27
Q
V
E
R
L
E
D
Y
Q
N
N
T
D
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NGC3
995
108026
I607
N
S
N
S
Q
T
F
I
A
G
E
V
A
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6C3
776
87784
I377
I
D
L
R
T
S
L
I
K
L
D
A
E
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.3
56.4
49.8
N.A.
52.5
28.5
N.A.
N.A.
N.A.
48.3
22
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
64.2
66.6
58.5
N.A.
62.1
39.2
N.A.
N.A.
N.A.
59.4
34.3
N.A.
41.7
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
20
N.A.
20
20
N.A.
N.A.
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% C
% Asp:
10
10
0
0
10
10
20
0
0
0
50
10
10
10
0
% D
% Glu:
0
0
10
0
0
10
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
10
0
10
0
0
0
10
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
40
0
0
0
0
0
30
0
0
0
0
0
30
0
% I
% Lys:
0
0
10
20
0
0
0
10
60
0
0
0
0
0
10
% K
% Leu:
0
10
10
10
10
0
10
0
0
70
0
0
0
0
0
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
10
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
40
0
0
0
50
50
40
0
% P
% Gln:
10
0
0
0
20
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
20
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
40
10
50
50
10
10
50
0
0
0
20
0
20
10
60
% S
% Thr:
0
10
0
0
40
50
0
10
0
0
0
20
0
0
10
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _