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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGAP8 All Species: 17.88
Human Site: T595 Identified Species: 43.7
UniProt: Q5SRD3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SRD3 NP_001071154.1 663 73068 T595 S R E E V N E T C G E G D G C
Chimpanzee Pan troglodytes XP_001141446 439 48772 G377 E T C G E G D G C T T L H L A
Rhesus Macaque Macaca mulatta XP_001082744 804 89081 T710 S R D E V N E T C G E G D G R
Dog Lupus familis XP_848466 936 102470 T842 S R E E V N E T C G E G D G R
Cat Felis silvestris
Mouse Mus musculus Q8BXK8 857 94393 T763 S R D E V N E T C G E G D G R
Rat Rattus norvegicus Q8CGU4 1186 124419 S1079 R H G P L D T S V E D P Q L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRL1 864 95088 T766 S R E E V N E T C G E G D R R
Zebra Danio Brachydanio rerio Q08CI4 339 38765 L276 Y A K Y Y F D L R S L A D D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NGC3 995 108026 E856 I L A N C P S E V T N A N V S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6C3 776 87784 R626 R N I R D I Y R L I V K A D A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.3 56.4 49.8 N.A. 52.5 28.5 N.A. N.A. N.A. 48.3 22 N.A. 29.4 N.A. N.A. N.A.
Protein Similarity: 100 64.2 66.6 58.5 N.A. 62.1 39.2 N.A. N.A. N.A. 59.4 34.3 N.A. 41.7 N.A. N.A. N.A.
P-Site Identity: 100 6.6 86.6 93.3 N.A. 86.6 0 N.A. N.A. N.A. 86.6 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 93.3 93.3 N.A. 93.3 26.6 N.A. N.A. N.A. 86.6 20 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 0 0 0 0 20 10 0 20 % A
% Cys: 0 0 10 0 10 0 0 0 60 0 0 0 0 0 10 % C
% Asp: 0 0 20 0 10 10 20 0 0 0 10 0 60 20 0 % D
% Glu: 10 0 30 50 10 0 50 10 0 10 50 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 10 0 10 0 50 0 50 0 40 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 10 0 0 10 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 10 0 0 10 10 0 10 10 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 50 0 0 0 0 10 0 10 0 10 % N
% Pro: 0 0 0 10 0 10 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 20 50 0 10 0 0 0 10 10 0 0 0 0 10 50 % R
% Ser: 50 0 0 0 0 0 10 10 0 10 0 0 0 0 10 % S
% Thr: 0 10 0 0 0 0 10 50 0 20 10 0 0 0 0 % T
% Val: 0 0 0 0 50 0 0 0 20 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 10 10 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _