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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP188 All Species: 18.18
Human Site: T1549 Identified Species: 44.44
UniProt: Q5SRE5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SRE5 NP_056169.1 1749 196043 T1549 S E Q Q A L H T V Q Y G L L K
Chimpanzee Pan troglodytes XP_520414 1750 196187 T1550 S E Q R A L H T V Q Y G L L K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548428 1752 196194 T1552 S E Q R A L H T V Q Y G L L K
Cat Felis silvestris
Mouse Mus musculus Q6ZQH8 1759 196677 T1559 S E Q R A L H T V Q Y G L L K
Rat Rattus norvegicus XP_345336 1753 196344 T1553 S E Q R A L H T V Q Y G L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510577 837 92873 A655 A K A K V F S A L I T I L Q M
Chicken Gallus gallus NP_001025861 1736 194813 M1539 A E Q K A L L M V Q Y S L L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923018 1732 194189 A1538 A E S K A L Q A V Q C S L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394949 1878 216662 H1600 Q L F T Q A L H Y R S Q P I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786945 1898 211849 A1684 D A S I S D D A Q E V Q L L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 95.3 N.A. 94 94.4 N.A. 43.8 85.3 N.A. 71.2 N.A. N.A. 21.8 N.A. 32.4
Protein Similarity: 100 99.7 N.A. 97.8 N.A. 96.9 97.4 N.A. 45.9 92.3 N.A. 83.3 N.A. N.A. 41.5 N.A. 52.1
P-Site Identity: 100 93.3 N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 66.6 N.A. 53.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 33.3 80 N.A. 66.6 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 10 10 0 70 10 0 30 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 70 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % G
% His: 0 0 0 0 0 0 50 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 10 0 10 0 10 0 % I
% Lys: 0 10 0 30 0 0 0 0 0 0 0 0 0 0 70 % K
% Leu: 0 10 0 0 0 70 20 0 10 0 0 0 90 80 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 10 0 60 10 10 0 10 0 10 70 0 20 0 10 0 % Q
% Arg: 0 0 0 40 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 50 0 20 0 10 0 10 0 0 0 10 20 0 0 10 % S
% Thr: 0 0 0 10 0 0 0 50 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 70 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 60 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _