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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYHD1 All Species: 30.91
Human Site: S199 Identified Species: 68
UniProt: Q5SRE7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SRE7 NP_001094346.1 291 32411 S199 G S H T S G V S R R M V R A P
Chimpanzee Pan troglodytes XP_001161929 291 32422 S199 G S H T S G V S R R M V R A P
Rhesus Macaque Macaca mulatta XP_001109799 288 31863 S199 G S H T S G V S R R M V R A P
Dog Lupus familis XP_851122 312 35179 S220 G S H T G G V S R R M V R A F
Cat Felis silvestris
Mouse Mus musculus Q9DB26 291 32499 S199 G S H T R G V S R R M I R A P
Rat Rattus norvegicus Q5BJP9 291 32535 S199 G S H T S G V S R R M I R A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415483 291 32692 T199 G S H T S G I T R R M V R A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U3U0 291 33175 T199 G S H N D G I T R R M V R T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAM7 288 33002 S192 G S H K D T S S A N Y R F V R
Sea Urchin Strong. purpuratus XP_789562 222 25262 D134 I T T R M V K D P D G T A T F
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141316 282 31665 L194 P G S H K K G L V R R M V R D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.8 81.7 N.A. 85.9 87.2 N.A. N.A. 71.1 N.A. 64.9 N.A. N.A. N.A. 46.7 41.5
Protein Similarity: 100 99.6 96.2 86.8 N.A. 92.4 93.1 N.A. N.A. 82.8 N.A. 80 N.A. N.A. N.A. 65.6 55.6
P-Site Identity: 100 100 100 86.6 N.A. 86.6 93.3 N.A. N.A. 80 N.A. 66.6 N.A. N.A. N.A. 26.6 0
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 100 N.A. N.A. 93.3 N.A. 80 N.A. N.A. N.A. 26.6 6.6
Percent
Protein Identity: N.A. 47.7 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 62.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 10 64 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 19 0 0 10 0 10 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 19 % F
% Gly: 82 10 0 0 10 73 10 0 0 0 10 0 0 0 0 % G
% His: 0 0 82 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 19 0 0 0 0 19 0 0 0 % I
% Lys: 0 0 0 10 10 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 73 10 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 55 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 0 0 0 73 82 10 10 73 10 10 % R
% Ser: 0 82 10 0 46 0 10 64 0 0 0 0 0 0 0 % S
% Thr: 0 10 10 64 0 10 0 19 0 0 0 10 0 19 0 % T
% Val: 0 0 0 0 0 10 55 0 10 0 0 55 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _