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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHYHD1 All Species: 31.82
Human Site: Y260 Identified Species: 70
UniProt: Q5SRE7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SRE7 NP_001094346.1 291 32411 Y260 S D R S R Q A Y T F H L M E A
Chimpanzee Pan troglodytes XP_001161929 291 32422 Y260 S D R S R Q A Y T F H L M E A
Rhesus Macaque Macaca mulatta XP_001109799 288 31863 Y257 S D H S R Q A Y T F H L M E A
Dog Lupus familis XP_851122 312 35179 Y281 S D R S R H A Y T F H L M E S
Cat Felis silvestris
Mouse Mus musculus Q9DB26 291 32499 Y260 S D H S R Q A Y T V H L M E A
Rat Rattus norvegicus Q5BJP9 291 32535 Y260 S D H S R Q A Y T F H L M E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415483 291 32692 Y260 S A F S R H V Y T F H V M E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U3U0 291 33175 Y260 S D A S R H V Y T F H I M E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAM7 288 33002 Y256 S E K S R H A Y T I H V M E R
Sea Urchin Strong. purpuratus XP_789562 222 25262 H192 S R H I Y T F H V A E S E N T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141316 282 31665 F252 S P A S R H A F S L H V V D T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.8 81.7 N.A. 85.9 87.2 N.A. N.A. 71.1 N.A. 64.9 N.A. N.A. N.A. 46.7 41.5
Protein Similarity: 100 99.6 96.2 86.8 N.A. 92.4 93.1 N.A. N.A. 82.8 N.A. 80 N.A. N.A. N.A. 65.6 55.6
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 93.3 N.A. N.A. 66.6 N.A. 66.6 N.A. N.A. N.A. 60 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 93.3 N.A. N.A. 73.3 N.A. 80 N.A. N.A. N.A. 80 13.3
Percent
Protein Identity: N.A. 47.7 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 62.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 66.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 0 0 73 0 0 10 0 0 0 0 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 64 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 10 0 10 82 0 % E
% Phe: 0 0 10 0 0 0 10 10 0 64 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 37 0 0 46 0 10 0 0 91 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 55 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 46 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 28 0 91 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 100 0 0 91 0 0 0 0 10 0 0 10 0 0 19 % S
% Thr: 0 0 0 0 0 10 0 0 82 0 0 0 0 0 19 % T
% Val: 0 0 0 0 0 0 19 0 10 10 0 28 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _