KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC39A
All Species:
16.36
Human Site:
S448
Identified Species:
32.73
UniProt:
Q5SRH9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SRH9
NP_001073963.1
613
69778
S448
K
S
R
R
Y
F
S
S
N
P
I
S
L
P
V
Chimpanzee
Pan troglodytes
XP_513400
577
65433
S412
K
S
R
R
Y
F
S
S
N
P
I
S
L
P
V
Rhesus Macaque
Macaca mulatta
XP_001111084
578
66105
S413
K
S
R
R
Y
L
S
S
K
P
I
S
L
P
V
Dog
Lupus familis
XP_531937
609
69528
P455
R
R
Y
S
A
S
L
P
A
P
V
K
L
I
V
Cat
Felis silvestris
Mouse
Mus musculus
A2ACP1
578
66108
P413
K
S
R
R
Y
L
S
P
N
P
I
S
L
P
I
Rat
Rattus norvegicus
Q0VGK2
522
58959
E373
Q
F
S
V
K
K
A
E
R
F
R
K
Q
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507830
616
70203
P459
K
S
R
R
Y
S
S
P
Q
P
V
K
L
I
L
Chicken
Gallus gallus
XP_422466
573
65249
S409
K
A
R
R
Y
L
S
S
N
P
V
P
L
P
V
Frog
Xenopus laevis
Q5XHH9
586
66802
D425
K
S
R
R
Y
I
S
D
N
P
V
K
L
T
L
Zebra Danio
Brachydanio rerio
A1A5Y5
565
64737
S404
K
A
R
R
Y
K
A
S
N
P
V
R
L
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09266
578
66748
A424
E
K
Y
C
G
R
K
A
K
R
F
T
T
T
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA06
811
88862
L628
V
K
A
Y
G
L
D
L
A
D
V
I
C
V
S
Conservation
Percent
Protein Identity:
100
92.8
92.5
44.2
N.A.
87.9
23
N.A.
45.2
71.2
50.4
57.9
N.A.
N.A.
N.A.
31.6
N.A.
Protein Similarity:
100
92.9
93.3
59.8
N.A.
91.3
43.3
N.A.
61.6
80.9
68.3
72
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
100
100
86.6
20
N.A.
80
0
N.A.
53.3
73.3
60
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
86.6
33.3
N.A.
86.6
13.3
N.A.
66.6
86.6
73.3
86.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
9
0
17
9
17
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
9
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
17
0
0
0
9
9
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
34
9
0
17
9
% I
% Lys:
67
17
0
0
9
17
9
0
17
0
0
34
0
0
0
% K
% Leu:
0
0
0
0
0
34
9
9
0
0
0
0
75
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
25
0
75
0
9
0
50
9
% P
% Gln:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% Q
% Arg:
9
9
67
67
0
9
0
0
9
9
9
9
0
0
0
% R
% Ser:
0
50
9
9
0
17
59
42
0
0
0
34
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
9
25
0
% T
% Val:
9
0
0
9
0
0
0
0
0
0
50
0
0
9
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
9
67
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _