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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VARS2 All Species: 20.3
Human Site: S37 Identified Species: 40.61
UniProt: Q5ST30 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5ST30 NP_065175.3 1063 118462 S37 T Q S E P H G S P I S R R N R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5TM74 1064 118624 S37 T Q S E P H G S P I S R R N R
Dog Lupus familis XP_532063 1077 119793 S52 T Q S E P C R S S L S R R N H
Cat Felis silvestris
Mouse Mus musculus Q3U2A8 1060 118361 S37 T Q P E P H G S P V S R R N R
Rat Rattus norvegicus Q6MG21 1065 118876 S37 T Q P E P H G S P V S R R N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres P49696 1217 138200 K179 A A L N G P P K T E A Q L K K
Fruit Fly Dros. melanogaster NP_524838 1049 118236 K39 L K A E K L A K L Q A K L D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1Q4 1050 118902 A41 K L A E K K A A A S D K P V K
Sea Urchin Strong. purpuratus XP_001200958 1119 126755 T89 S S P G V D S T S S G A G D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93736 1108 125908 T54 E S E K K I L T E E E L E R K
Baker's Yeast Sacchar. cerevisiae P07806 1104 125751 S73 N P L K E D G S P K T P K E I
Red Bread Mold Neurospora crassa P28350 1093 123334 A57 P A A A P A A A P A A Q D A P
Conservation
Percent
Protein Identity: 100 N.A. 95.5 84.3 N.A. 84 83.4 N.A. N.A. N.A. N.A. N.A. 42.4 46.3 N.A. 43.6 45.6
Protein Similarity: 100 N.A. 96.9 89.1 N.A. 89.6 89 N.A. N.A. N.A. N.A. N.A. 57.9 62 N.A. 61.1 60.1
P-Site Identity: 100 N.A. 100 66.6 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. N.A. 0 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 N.A. 100 73.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. 20 46.6 N.A. 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 43.5 39.9 39.8
Protein Similarity: N.A. N.A. N.A. 59.6 58.1 57.3
P-Site Identity: N.A. N.A. N.A. 0 20 13.3
P-Site Similarity: N.A. N.A. N.A. 20 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 25 9 0 9 25 17 9 9 25 9 0 9 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 17 0 0 0 0 9 0 9 17 0 % D
% Glu: 9 0 9 59 9 0 0 0 9 17 9 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 0 42 0 0 0 9 0 9 0 0 % G
% His: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 9 % I
% Lys: 9 9 0 17 25 9 0 17 0 9 0 17 9 9 34 % K
% Leu: 9 9 17 0 0 9 9 0 9 9 0 9 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 0 0 0 0 0 0 0 0 0 42 0 % N
% Pro: 9 9 25 0 50 9 9 0 50 0 0 9 9 0 9 % P
% Gln: 0 42 0 0 0 0 0 0 0 9 0 17 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 42 42 9 42 % R
% Ser: 9 17 25 0 0 0 9 50 17 17 42 0 0 0 0 % S
% Thr: 42 0 0 0 0 0 0 17 9 0 9 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 17 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _