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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VARS2 All Species: 15.76
Human Site: S879 Identified Species: 31.52
UniProt: Q5ST30 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5ST30 NP_065175.3 1063 118462 S879 P G C P P A P S I S V A P Y P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5TM74 1064 118624 S880 P G C P P A P S I S V A P Y P
Dog Lupus familis XP_532063 1077 119793 S895 P G S N S A P S I S V A P Y P
Cat Felis silvestris
Mouse Mus musculus Q3U2A8 1060 118361 S880 P G G P L A P S I C V A P Y P
Rat Rattus norvegicus Q6MG21 1065 118876 P885 A P S I C V A P Y P S G H S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres P49696 1217 138200 P1037 R R P Q S D P P S I C V T P Y
Fruit Fly Dros. melanogaster NP_524838 1049 118236 P872 Q R L P R A N P A P S I C V A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1Q4 1050 118902 S868 D S D Y T S P S I I V A Q Y P
Sea Urchin Strong. purpuratus XP_001200958 1119 126755 R933 E L F Q R L P R Q Q N D E C P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93736 1108 125908 K919 A P K D T E R K A S I M I C D
Baker's Yeast Sacchar. cerevisiae P07806 1104 125751 A923 P K R S T E K A A S I V K A S
Red Bread Mold Neurospora crassa P28350 1093 123334 Y895 L L H P I M P Y I T E E L W Q
Conservation
Percent
Protein Identity: 100 N.A. 95.5 84.3 N.A. 84 83.4 N.A. N.A. N.A. N.A. N.A. 42.4 46.3 N.A. 43.6 45.6
Protein Similarity: 100 N.A. 96.9 89.1 N.A. 89.6 89 N.A. N.A. N.A. N.A. N.A. 57.9 62 N.A. 61.1 60.1
P-Site Identity: 100 N.A. 100 80 N.A. 80 0 N.A. N.A. N.A. N.A. N.A. 6.6 13.3 N.A. 46.6 13.3
P-Site Similarity: 100 N.A. 100 80 N.A. 80 0 N.A. N.A. N.A. N.A. N.A. 6.6 13.3 N.A. 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 43.5 39.9 39.8
Protein Similarity: N.A. N.A. N.A. 59.6 58.1 57.3
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 20
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 42 9 9 25 0 0 42 0 9 9 % A
% Cys: 0 0 17 0 9 0 0 0 0 9 9 0 9 17 0 % C
% Asp: 9 0 9 9 0 9 0 0 0 0 0 9 0 0 9 % D
% Glu: 9 0 0 0 0 17 0 0 0 0 9 9 9 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 34 9 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 50 17 17 9 9 0 0 % I
% Lys: 0 9 9 0 0 0 9 9 0 0 0 0 9 0 0 % K
% Leu: 9 17 9 0 9 9 0 0 0 0 0 0 9 0 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 9 0 0 9 0 0 0 9 0 0 0 0 % N
% Pro: 42 17 9 42 17 0 67 25 0 17 0 0 34 9 50 % P
% Gln: 9 0 0 17 0 0 0 0 9 9 0 0 9 0 9 % Q
% Arg: 9 17 9 0 17 0 9 9 0 0 0 0 0 0 0 % R
% Ser: 0 9 17 9 17 9 0 42 9 42 17 0 0 9 9 % S
% Thr: 0 0 0 0 25 0 0 0 0 9 0 0 9 0 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 42 17 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 9 0 0 0 9 9 0 0 0 0 42 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _