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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VARS2 All Species: 20.91
Human Site: S97 Identified Species: 41.82
UniProt: Q5ST30 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5ST30 NP_065175.3 1063 118462 S97 P G E K K D V S G P L P P A Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5TM74 1064 118624 S97 P G E K K D V S G P L P P A Y
Dog Lupus familis XP_532063 1077 119793 Y112 P G E K K D V Y R L L P P A Y
Cat Felis silvestris
Mouse Mus musculus Q3U2A8 1060 118361 S97 P G E K K D V S G P L P P A Y
Rat Rattus norvegicus Q6MG21 1065 118876 S97 P G E K K D V S G P L P P A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres P49696 1217 138200 V242 S G E K K D V V S P L P D S Y
Fruit Fly Dros. melanogaster NP_524838 1049 118236 R97 L P D A Y S P R Y V E A Q W Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1Q4 1050 118902 K103 W E K E G F F K P E Y I D K L
Sea Urchin Strong. purpuratus XP_001200958 1119 126755 S155 P G E K K D V S V A L P R S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93736 1108 125908 E128 D P E T P L G E R K R L S S Q
Baker's Yeast Sacchar. cerevisiae P07806 1104 125751 D141 K K I L V S L D D P A L K A Y
Red Bread Mold Neurospora crassa P28350 1093 123334 Q130 A G E K K V I Q S F E H P H F
Conservation
Percent
Protein Identity: 100 N.A. 95.5 84.3 N.A. 84 83.4 N.A. N.A. N.A. N.A. N.A. 42.4 46.3 N.A. 43.6 45.6
Protein Similarity: 100 N.A. 96.9 89.1 N.A. 89.6 89 N.A. N.A. N.A. N.A. N.A. 57.9 62 N.A. 61.1 60.1
P-Site Identity: 100 N.A. 100 80 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. 66.6 6.6 N.A. 0 73.3
P-Site Similarity: 100 N.A. 100 80 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. 73.3 13.3 N.A. 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. 43.5 39.9 39.8
Protein Similarity: N.A. N.A. N.A. 59.6 58.1 57.3
P-Site Identity: N.A. N.A. N.A. 6.6 20 33.3
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 0 0 0 9 9 9 0 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 59 0 9 9 0 0 0 17 0 0 % D
% Glu: 0 9 75 9 0 0 0 9 0 9 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 9 0 0 9 0 0 0 0 9 % F
% Gly: 0 67 0 0 9 0 9 0 34 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % H
% Ile: 0 0 9 0 0 0 9 0 0 0 0 9 0 0 0 % I
% Lys: 9 9 9 67 67 0 0 9 0 9 0 0 9 9 0 % K
% Leu: 9 0 0 9 0 9 9 0 0 9 59 17 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 17 0 0 9 0 9 0 9 50 0 59 50 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 9 % Q
% Arg: 0 0 0 0 0 0 0 9 17 0 9 0 9 0 0 % R
% Ser: 9 0 0 0 0 17 0 42 17 0 0 0 9 25 0 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 9 59 9 9 9 0 0 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 9 0 0 9 9 0 9 0 0 0 75 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _