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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VARS2 All Species: 27.58
Human Site: Y104 Identified Species: 55.15
UniProt: Q5ST30 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5ST30 NP_065175.3 1063 118462 Y104 S G P L P P A Y S P R Y V E A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5TM74 1064 118624 Y104 S G P L P P A Y S P R Y V E A
Dog Lupus familis XP_532063 1077 119793 Y119 Y R L L P P A Y S P R Y V E A
Cat Felis silvestris
Mouse Mus musculus Q3U2A8 1060 118361 Y104 S G P L P P A Y S P Q Y V E A
Rat Rattus norvegicus Q6MG21 1065 118876 Y104 S G P L P P A Y S P Q Y V E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres P49696 1217 138200 Y249 V S P L P D S Y S P Q Y V E A
Fruit Fly Dros. melanogaster NP_524838 1049 118236 Y104 R Y V E A Q W Y S W W E K E G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1Q4 1050 118902 L110 K P E Y I D K L N P G S N P A
Sea Urchin Strong. purpuratus XP_001200958 1119 126755 Y162 S V A L P R S Y S P S Y V E A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93736 1108 125908 Q135 E R K R L S S Q M A K Q Y S P
Baker's Yeast Sacchar. cerevisiae P07806 1104 125751 Y148 D D P A L K A Y N P A N V E S
Red Bread Mold Neurospora crassa P28350 1093 123334 F137 Q S F E H P H F S A Y N P S A
Conservation
Percent
Protein Identity: 100 N.A. 95.5 84.3 N.A. 84 83.4 N.A. N.A. N.A. N.A. N.A. 42.4 46.3 N.A. 43.6 45.6
Protein Similarity: 100 N.A. 96.9 89.1 N.A. 89.6 89 N.A. N.A. N.A. N.A. N.A. 57.9 62 N.A. 61.1 60.1
P-Site Identity: 100 N.A. 100 80 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. 66.6 20 N.A. 13.3 66.6
P-Site Similarity: 100 N.A. 100 80 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. 80 20 N.A. 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 43.5 39.9 39.8
Protein Similarity: N.A. N.A. N.A. 59.6 58.1 57.3
P-Site Identity: N.A. N.A. N.A. 0 40 20
P-Site Similarity: N.A. N.A. N.A. 13.3 53.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 0 50 0 0 17 9 0 0 0 75 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 0 17 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 9 17 0 0 0 0 0 0 0 9 0 75 0 % E
% Phe: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 34 0 0 0 0 0 0 0 0 9 0 0 0 9 % G
% His: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 9 0 0 9 9 0 0 0 9 0 9 0 0 % K
% Leu: 0 0 9 59 17 0 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 17 0 0 17 9 0 0 % N
% Pro: 0 9 50 0 59 50 0 0 0 75 0 0 9 9 9 % P
% Gln: 9 0 0 0 0 9 0 9 0 0 25 9 0 0 0 % Q
% Arg: 9 17 0 9 0 9 0 0 0 0 25 0 0 0 0 % R
% Ser: 42 17 0 0 0 9 25 0 75 0 9 9 0 17 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 9 9 9 0 0 0 0 0 0 0 0 0 67 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 9 9 0 0 0 0 % W
% Tyr: 9 9 0 9 0 0 0 75 0 0 9 59 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _