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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DACT2
All Species:
6.36
Human Site:
S451
Identified Species:
20
UniProt:
Q5SW24
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SW24
NP_999627.2
774
82700
S451
S
K
A
Q
Q
T
P
S
A
Q
D
Y
G
R
G
Chimpanzee
Pan troglodytes
XP_001145122
892
95001
S569
S
K
A
Q
Q
T
P
S
A
Q
D
Y
G
R
G
Rhesus Macaque
Macaca mulatta
XP_001083736
773
82686
P450
L
K
A
Q
Q
T
P
P
A
Q
D
C
G
R
G
Dog
Lupus familis
XP_855310
817
86010
L434
V
Y
P
Y
P
S
P
L
H
A
V
A
L
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN08
757
81650
N432
S
Q
A
Q
Q
P
L
N
D
C
G
Q
G
P
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512031
313
33112
Q16
G
L
K
S
H
L
D
Q
L
D
Q
Q
I
N
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8QG92
824
90939
V442
S
R
N
T
V
K
S
V
C
Q
G
L
A
R
G
Zebra Danio
Brachydanio rerio
Q673G8
837
91276
T482
V
E
R
K
S
S
F
T
S
G
R
E
G
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68
93
28.1
N.A.
56.4
N.A.
N.A.
23.8
N.A.
21.6
33.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.6
95
38
N.A.
66.2
N.A.
N.A.
29.8
N.A.
37.1
43.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
33.3
N.A.
N.A.
0
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
20
N.A.
46.6
N.A.
N.A.
0
N.A.
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
0
38
13
0
13
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
13
13
0
13
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
13
13
38
0
0
0
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
0
13
0
0
13
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
13
25
0
63
0
50
% G
% His:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
38
13
13
0
13
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
13
0
0
0
13
13
13
13
0
0
13
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
13
0
0
0
0
0
13
0
% N
% Pro:
0
0
13
0
13
13
50
13
0
0
0
0
0
13
0
% P
% Gln:
0
13
0
50
50
0
0
13
0
50
13
25
0
13
0
% Q
% Arg:
0
13
13
0
0
0
0
0
0
0
13
0
0
50
13
% R
% Ser:
50
0
0
13
13
25
13
25
13
0
0
0
0
13
13
% S
% Thr:
0
0
0
13
0
38
0
13
0
0
0
0
0
0
0
% T
% Val:
25
0
0
0
13
0
0
13
0
0
13
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
13
0
0
0
0
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _