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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LDLRAP1
All Species:
9.09
Human Site:
S175
Identified Species:
22.22
UniProt:
Q5SW96
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SW96
NP_056442.2
308
33885
S175
A
F
E
F
W
Q
V
S
K
E
E
K
E
K
R
Chimpanzee
Pan troglodytes
XP_001145086
261
28665
F129
D
K
M
H
D
K
V
F
A
Y
I
A
Q
S
Q
Rhesus Macaque
Macaca mulatta
XP_001107620
308
33839
S175
A
F
E
F
W
Q
V
S
K
E
E
K
E
K
R
Dog
Lupus familis
XP_855049
309
33983
S175
A
F
E
F
W
Q
V
S
K
E
E
K
E
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C142
308
33927
K175
F
E
F
W
Q
V
S
K
E
E
K
E
K
R
E
Rat
Rattus norvegicus
Q5PQS4
304
34267
R172
Q
I
A
G
M
Q
K
R
I
Q
D
L
E
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417736
307
33801
K175
F
E
F
W
Q
A
S
K
E
E
K
E
K
R
E
Frog
Xenopus laevis
Q67FQ3
309
34222
E176
E
F
W
Q
V
S
R
E
N
K
D
K
R
E
K
Zebra Danio
Brachydanio rerio
Q32PV0
300
33841
G167
V
E
T
R
K
Q
I
G
G
L
Q
K
R
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122880
120
13239
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
97.7
93.8
N.A.
89.2
25
N.A.
N.A.
73
71.1
23
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
100
84.4
99
97
N.A.
95.1
44.4
N.A.
N.A.
83.1
84.1
39.9
N.A.
N.A.
33.4
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
6.6
13.3
N.A.
N.A.
6.6
13.3
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
46.6
26.6
N.A.
N.A.
46.6
40
33.3
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
10
0
0
10
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
20
0
0
0
0
% D
% Glu:
10
30
30
0
0
0
0
10
20
50
30
20
40
10
30
% E
% Phe:
20
40
20
30
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
10
0
10
0
0
10
0
% I
% Lys:
0
10
0
0
10
10
10
20
30
10
20
50
20
30
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% L
% Met:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
10
20
50
0
0
0
10
10
0
10
0
20
% Q
% Arg:
0
0
0
10
0
0
10
10
0
0
0
0
20
20
30
% R
% Ser:
0
0
0
0
0
10
20
30
0
0
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
10
10
40
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
20
30
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _