KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R15B
All Species:
14.55
Human Site:
S440
Identified Species:
40
UniProt:
Q5SWA1
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SWA1
NP_116222.3
713
79152
S440
A
S
S
D
L
E
T
S
S
D
P
E
G
E
D
Chimpanzee
Pan troglodytes
XP_001159260
713
79042
S440
A
S
S
D
L
E
T
S
S
D
P
E
G
E
D
Rhesus Macaque
Macaca mulatta
XP_001097695
710
78870
S437
A
S
S
D
L
E
T
S
S
D
P
E
G
E
D
Dog
Lupus familis
XP_545680
848
92698
S570
Y
I
L
G
G
T
S
S
D
L
E
T
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFW3
697
77694
S424
A
P
S
D
L
E
A
S
S
D
S
E
S
E
D
Rat
Rattus norvegicus
NP_001100645
707
78800
G434
D
E
E
P
E
D
D
G
F
D
S
D
G
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506847
523
57154
E268
S
E
G
E
D
W
D
E
E
E
E
D
A
G
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088578
471
53886
N216
E
G
E
Q
L
W
E
N
E
E
E
S
C
F
A
Zebra Danio
Brachydanio rerio
NP_001038684
441
49493
S186
H
F
S
D
S
E
F
S
W
G
S
T
D
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
92.9
54.1
N.A.
67.7
67.5
N.A.
39.1
N.A.
22.7
20.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
95.5
62.7
N.A.
75.4
76.7
N.A.
48.9
N.A.
37
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
73.3
13.3
N.A.
0
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
73.3
26.6
N.A.
26.6
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
0
0
0
12
0
0
0
0
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
0
0
56
12
12
23
0
12
56
0
23
12
0
56
% D
% Glu:
12
23
23
12
12
56
12
12
23
23
34
45
0
45
0
% E
% Phe:
0
12
0
0
0
0
12
0
12
0
0
0
0
12
12
% F
% Gly:
0
12
12
12
12
0
0
12
0
12
0
0
45
12
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
56
0
0
0
0
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
12
0
0
0
0
0
0
34
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
34
56
0
12
0
12
67
45
0
34
12
23
34
12
% S
% Thr:
0
0
0
0
0
12
34
0
0
0
0
23
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
23
0
0
12
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _