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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R15B
All Species:
14.24
Human Site:
S466
Identified Species:
39.17
UniProt:
Q5SWA1
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SWA1
NP_116222.3
713
79152
S466
S
D
S
S
L
S
D
S
D
L
E
Q
D
P
E
Chimpanzee
Pan troglodytes
XP_001159260
713
79042
S466
S
D
S
S
L
S
D
S
D
L
E
Q
D
P
E
Rhesus Macaque
Macaca mulatta
XP_001097695
710
78870
S463
S
D
S
S
L
S
D
S
D
L
E
Q
D
P
E
Dog
Lupus familis
XP_545680
848
92698
S601
S
D
S
P
L
S
A
S
D
L
E
Q
D
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFW3
697
77694
E449
D
S
D
G
S
L
S
E
S
D
V
E
Q
D
S
Rat
Rattus norvegicus
NP_001100645
707
78800
Q475
Q
N
F
T
A
T
I
Q
T
A
A
R
I
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506847
523
57154
S291
P
G
P
G
Q
R
D
S
V
L
W
R
S
F
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088578
471
53886
P239
G
M
Q
E
P
W
T
P
G
S
K
N
Y
T
E
Zebra Danio
Brachydanio rerio
NP_001038684
441
49493
L209
S
D
K
L
W
D
L
L
T
K
S
T
D
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
92.9
54.1
N.A.
67.7
67.5
N.A.
39.1
N.A.
22.7
20.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
95.5
62.7
N.A.
75.4
76.7
N.A.
48.9
N.A.
37
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
0
0
N.A.
20
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
6.6
26.6
N.A.
26.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
0
0
12
12
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
12
56
12
0
0
12
45
0
45
12
0
0
56
12
0
% D
% Glu:
0
0
0
12
0
0
0
12
0
0
45
12
0
0
56
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
12
0
23
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
12
12
0
0
0
0
% K
% Leu:
0
0
0
12
45
12
12
12
0
56
0
0
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
12
0
12
12
12
0
0
12
0
0
0
0
0
56
12
% P
% Gln:
12
0
12
0
12
0
0
12
0
0
0
45
12
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
0
23
0
0
0
% R
% Ser:
56
12
45
34
12
45
12
56
12
12
12
0
12
0
12
% S
% Thr:
0
0
0
12
0
12
12
0
23
0
0
12
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _