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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM69
All Species:
4.55
Human Site:
S235
Identified Species:
20
UniProt:
Q5SWH9
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SWH9
NP_057570.2
247
27551
S235
I
T
L
V
V
K
S
S
F
P
E
K
G
H
K
Chimpanzee
Pan troglodytes
XP_513137
247
27632
S235
I
T
L
V
V
K
S
S
F
P
E
K
G
H
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3KQJ0
245
27294
I235
V
T
L
I
L
E
N
I
Y
P
E
K
G
P
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508599
278
30318
L266
A
T
L
L
L
Q
D
L
Y
P
E
K
G
P
K
Chicken
Gallus gallus
XP_422441
297
33120
V280
T
T
L
A
V
K
M
V
S
E
N
E
L
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791059
168
17902
I161
N
F
K
K
L
I
K
I
A
Q
I
I
V
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
N.A.
N.A.
68.4
N.A.
N.A.
46.4
36.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20.2
Protein Similarity:
100
98.7
N.A.
N.A.
N.A.
78.9
N.A.
N.A.
62.5
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
29.5
P-Site Identity:
100
100
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
46.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
0
0
0
0
17
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
34
% D
% Glu:
0
0
0
0
0
17
0
0
0
17
67
17
0
0
0
% E
% Phe:
0
17
0
0
0
0
0
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% H
% Ile:
34
0
0
17
0
17
0
34
0
0
17
17
0
0
0
% I
% Lys:
0
0
17
17
0
50
17
0
0
0
0
67
0
0
67
% K
% Leu:
0
0
84
17
50
0
0
17
0
0
0
0
17
17
0
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
17
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
67
0
0
0
34
0
% P
% Gln:
0
0
0
0
0
17
0
0
0
17
0
0
0
17
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
34
34
17
0
0
0
0
0
0
% S
% Thr:
17
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
34
50
0
0
17
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _