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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLVS2 All Species: 13.03
Human Site: S302 Identified Species: 28.67
UniProt: Q5SYC1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SYC1 NP_001010852.2 327 38000 S302 K S M K R S Q S V V D P T V L
Chimpanzee Pan troglodytes XP_001158960 304 35294 Y276 D Y S D E N D Y T H T S Y N A
Rhesus Macaque Macaca mulatta XP_001091304 354 40742 M324 R E C S P K L M K R S Q S V V
Dog Lupus familis XP_544098 354 40730 M324 R E C S P K P M K R S Q S V V
Cat Felis silvestris
Mouse Mus musculus Q8BG92 327 37936 S302 K S M K R S Q S V V D P T A L
Rat Rattus norvegicus A6JUQ6 327 37898 S302 K S M K R S Q S V V D P T A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513318 344 39097 L321 R L A L R G L L G R Q D G G A
Chicken Gallus gallus XP_419223 332 38227 M302 Q E D S P K P M K R S Q S V V
Frog Xenopus laevis Q5M7E1 332 38511 M302 G E D S P K Y M K R S H S V V
Zebra Danio Brachydanio rerio Q5SPP0 329 38101 S302 K T M K R S Q S V V E P G V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCU1 409 46492 C370 K A T D E A V C N S F T T V E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.6 74.8 74.8 N.A. 97.8 98.7 N.A. 53.4 79.8 78.6 88.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 84 83 83 N.A. 99.6 99.3 N.A. 63.9 88.2 87.9 95.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 6.6 N.A. 93.3 93.3 N.A. 6.6 6.6 6.6 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 26.6 26.6 N.A. 93.3 93.3 N.A. 13.3 26.6 20 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 10 0 0 0 0 0 0 0 19 19 % A
% Cys: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 19 19 0 0 10 0 0 0 28 10 0 0 0 % D
% Glu: 0 37 0 0 19 0 0 0 0 0 10 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 0 0 0 0 10 0 0 10 0 0 0 19 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 46 0 0 37 0 37 0 0 37 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 0 0 19 10 0 0 0 0 0 0 37 % L
% Met: 0 0 37 0 0 0 0 37 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 37 0 19 0 0 0 0 37 0 0 0 % P
% Gln: 10 0 0 0 0 0 37 0 0 0 10 28 0 0 0 % Q
% Arg: 28 0 0 0 46 0 0 0 0 46 0 0 0 0 0 % R
% Ser: 0 28 10 37 0 37 0 37 0 10 37 10 37 0 0 % S
% Thr: 0 10 10 0 0 0 0 0 10 0 10 10 37 0 0 % T
% Val: 0 0 0 0 0 0 10 0 37 37 0 0 0 64 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _