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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLVS2
All Species:
32.73
Human Site:
T222
Identified Species:
72
UniProt:
Q5SYC1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SYC1
NP_001010852.2
327
38000
T222
R
P
F
L
K
E
K
T
R
K
R
I
F
L
H
Chimpanzee
Pan troglodytes
XP_001158960
304
35294
G196
D
S
F
P
A
R
F
G
G
V
H
F
V
N
Q
Rhesus Macaque
Macaca mulatta
XP_001091304
354
40742
T244
K
P
F
L
K
D
K
T
R
K
R
I
F
L
H
Dog
Lupus familis
XP_544098
354
40730
T244
K
P
F
L
K
D
K
T
R
K
R
I
F
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG92
327
37936
T222
R
P
F
L
K
E
K
T
R
K
R
I
F
L
H
Rat
Rattus norvegicus
A6JUQ6
327
37898
T222
R
P
F
L
K
E
K
T
R
K
R
I
F
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513318
344
39097
A241
T
P
S
I
L
K
L
A
I
E
G
L
Q
L
L
Chicken
Gallus gallus
XP_419223
332
38227
T222
K
P
F
L
K
D
K
T
R
K
R
I
F
L
H
Frog
Xenopus laevis
Q5M7E1
332
38511
T222
K
P
F
L
K
D
K
T
R
K
R
I
F
L
H
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
T222
R
P
F
L
K
D
K
T
R
K
R
I
F
M
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCU1
409
46492
S290
P
V
Q
Y
G
G
L
S
R
P
T
D
S
Q
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
74.8
74.8
N.A.
97.8
98.7
N.A.
53.4
79.8
78.6
88.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84
83
83
N.A.
99.6
99.3
N.A.
63.9
88.2
87.9
95.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
86.6
N.A.
100
100
N.A.
13.3
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
40
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
46
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
28
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
82
0
0
0
10
0
0
0
0
10
73
0
0
% F
% Gly:
0
0
0
0
10
10
0
10
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
73
% H
% Ile:
0
0
0
10
0
0
0
0
10
0
0
73
0
0
0
% I
% Lys:
37
0
0
0
73
10
73
0
0
73
0
0
0
0
0
% K
% Leu:
0
0
0
73
10
0
19
0
0
0
0
10
0
73
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
10
82
0
10
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
10
% Q
% Arg:
37
0
0
0
0
10
0
0
82
0
73
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
0
10
0
0
0
0
10
0
0
% S
% Thr:
10
0
0
0
0
0
0
73
0
0
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _